Replacement of the Left-Side Valves of an Implanted Total Artificial Heart
The MagScrew total artificial heart (TAH) is under development. Despite its anticipated durability and reliability, the possibility of a bioprosthetic valve malfunction exists. As a result, the potential for valve replacement surgery, instead of device replacement, would be desirable after a TAH imp...
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Veröffentlicht in: | ASAIO journal (1992) 2006-07, Vol.52 (4), p.368-372 |
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creator | Kamohara, Keiji Weber, Stephan Klatte, Ryan S Ootaki, Yoshio Akiyama, Masatoshi Kopcak, Michael W Luangphakdy, Viviane Flick, Christine R Chen, Ji-Feng Navia, Jose L Smith, William A Fukamachi, Kiyotaka |
description | The MagScrew total artificial heart (TAH) is under development. Despite its anticipated durability and reliability, the possibility of a bioprosthetic valve malfunction exists. As a result, the potential for valve replacement surgery, instead of device replacement, would be desirable after a TAH implant. In two of our 90-day animal experiments, we successfully replaced the left-side valves through a left thoracotomy opposite to the right-sided incision site for the initial TAH implant. The results of these cases suggest that the left-side valves could also be replaced through a left thoracotomy approach in humans. To confirm the ability to access the left-side valves in humans, four human cadaver studies were performed with the use of a mock pump designed for human application. This report describes the operative techniques for left-side valve replacement in animals and discusses the advantages of a left thoracotomy in clinical situations, based on results from the human cadaver studies. |
doi_str_mv | 10.1097/01.mat.0000227731.46835.1e |
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Despite its anticipated durability and reliability, the possibility of a bioprosthetic valve malfunction exists. As a result, the potential for valve replacement surgery, instead of device replacement, would be desirable after a TAH implant. In two of our 90-day animal experiments, we successfully replaced the left-side valves through a left thoracotomy opposite to the right-sided incision site for the initial TAH implant. The results of these cases suggest that the left-side valves could also be replaced through a left thoracotomy approach in humans. To confirm the ability to access the left-side valves in humans, four human cadaver studies were performed with the use of a mock pump designed for human application. This report describes the operative techniques for left-side valve replacement in animals and discusses the advantages of a left thoracotomy in clinical situations, based on results from the human cadaver studies.</description><identifier>ISSN: 1058-2916</identifier><identifier>EISSN: 1538-943X</identifier><identifier>DOI: 10.1097/01.mat.0000227731.46835.1e</identifier><identifier>PMID: 16883114</identifier><language>eng</language><publisher>United States: Copyright by the American Society for Artificial Internal Organs</publisher><subject>Animals ; Bioprosthesis ; Cattle ; Feasibility Studies ; Female ; Heart Valve Prosthesis ; Heart Valve Prosthesis Implantation - methods ; Heart, Artificial ; Humans ; Male ; Prostheses and Implants ; Prosthesis Design ; Prosthesis Failure ; Prosthesis Fitting ; Reoperation - methods ; Thoracotomy - methods ; Time Factors</subject><ispartof>ASAIO journal (1992), 2006-07, Vol.52 (4), p.368-372</ispartof><rights>Copyright © 2006 by the American Society for Artificial Internal Organs</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4143-70fd62b9e64c73792e4ef0a87445ae6155fd4adfe1770d6bde9c69405076eda33</citedby><cites>FETCH-LOGICAL-c4143-70fd62b9e64c73792e4ef0a87445ae6155fd4adfe1770d6bde9c69405076eda33</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf><![CDATA[$$Uhttp://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&PDF=y&D=ovft&AN=00002480-200607000-00003$$EPDF$$P50$$Gwolterskluwer$$H]]></linktopdf><linktohtml>$$Uhttp://ovidsp.ovid.com/ovidweb.cgi?T=JS&NEWS=n&CSC=Y&PAGE=fulltext&D=ovft&AN=00002480-200607000-00003$$EHTML$$P50$$Gwolterskluwer$$H</linktohtml><link.rule.ids>314,780,784,4609,27924,27925,64666,65461</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16883114$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Kamohara, Keiji</creatorcontrib><creatorcontrib>Weber, Stephan</creatorcontrib><creatorcontrib>Klatte, Ryan S</creatorcontrib><creatorcontrib>Ootaki, Yoshio</creatorcontrib><creatorcontrib>Akiyama, Masatoshi</creatorcontrib><creatorcontrib>Kopcak, Michael W</creatorcontrib><creatorcontrib>Luangphakdy, Viviane</creatorcontrib><creatorcontrib>Flick, Christine R</creatorcontrib><creatorcontrib>Chen, Ji-Feng</creatorcontrib><creatorcontrib>Navia, Jose L</creatorcontrib><creatorcontrib>Smith, William A</creatorcontrib><creatorcontrib>Fukamachi, Kiyotaka</creatorcontrib><title>Replacement of the Left-Side Valves of an Implanted Total Artificial Heart</title><title>ASAIO journal (1992)</title><addtitle>ASAIO J</addtitle><description>The MagScrew total artificial heart (TAH) is under development. Despite its anticipated durability and reliability, the possibility of a bioprosthetic valve malfunction exists. As a result, the potential for valve replacement surgery, instead of device replacement, would be desirable after a TAH implant. In two of our 90-day animal experiments, we successfully replaced the left-side valves through a left thoracotomy opposite to the right-sided incision site for the initial TAH implant. The results of these cases suggest that the left-side valves could also be replaced through a left thoracotomy approach in humans. To confirm the ability to access the left-side valves in humans, four human cadaver studies were performed with the use of a mock pump designed for human application. This report describes the operative techniques for left-side valve replacement in animals and discusses the advantages of a left thoracotomy in clinical situations, based on results from the human cadaver studies.</description><subject>Animals</subject><subject>Bioprosthesis</subject><subject>Cattle</subject><subject>Feasibility Studies</subject><subject>Female</subject><subject>Heart Valve Prosthesis</subject><subject>Heart Valve Prosthesis Implantation - methods</subject><subject>Heart, Artificial</subject><subject>Humans</subject><subject>Male</subject><subject>Prostheses and Implants</subject><subject>Prosthesis Design</subject><subject>Prosthesis Failure</subject><subject>Prosthesis Fitting</subject><subject>Reoperation - methods</subject><subject>Thoracotomy - methods</subject><subject>Time Factors</subject><issn>1058-2916</issn><issn>1538-943X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2006</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFkFtL7DAQgIMo3v-ClPPgW-tMkyatbyJeWRC84VvINhO22m73JFnFf2_WXTAvM5l8Mxk-xv4hFAiNOgMsBhMLSKcsleJYCFnzqkDaYvtY8TpvBH_bTjlUdV42KPfYQQjvAOmR4y7bQ1nXHFHss_tHWvSmpYHmMRtdFmeUTcjF_KmzlL2a_pPCqm7m2d2QyHkkmz2P0fTZhY-d69oupbdkfDxiO870gY438ZC9XF89X97mk4ebu8uLSd4KFDxX4Kwspw1J0SqumpIEOTC1EqIyJLGqnBXGOkKlwMqppaaVjYAKlCRrOD9kp-u5Cz_-X1KIeuhCS31ajsZl0LJWgEo0CTxfg60fQ_Dk9MJ3g_HfGkGvTGpAnUzqP5P616RGSs0nm1-W04HsX-tGXQLEGvga-0g-fPTLL_J6RqaPs_VIUUNeAkhQ6ZavSpz_ALozfyA</recordid><startdate>200607</startdate><enddate>200607</enddate><creator>Kamohara, Keiji</creator><creator>Weber, Stephan</creator><creator>Klatte, Ryan S</creator><creator>Ootaki, Yoshio</creator><creator>Akiyama, Masatoshi</creator><creator>Kopcak, Michael W</creator><creator>Luangphakdy, Viviane</creator><creator>Flick, Christine R</creator><creator>Chen, Ji-Feng</creator><creator>Navia, Jose L</creator><creator>Smith, William A</creator><creator>Fukamachi, Kiyotaka</creator><general>Copyright by the American Society for Artificial Internal Organs</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>200607</creationdate><title>Replacement of the Left-Side Valves of an Implanted Total Artificial Heart</title><author>Kamohara, Keiji ; Weber, Stephan ; Klatte, Ryan S ; Ootaki, Yoshio ; Akiyama, Masatoshi ; Kopcak, Michael W ; Luangphakdy, Viviane ; Flick, Christine R ; Chen, Ji-Feng ; Navia, Jose L ; Smith, William A ; Fukamachi, Kiyotaka</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4143-70fd62b9e64c73792e4ef0a87445ae6155fd4adfe1770d6bde9c69405076eda33</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2006</creationdate><topic>Animals</topic><topic>Bioprosthesis</topic><topic>Cattle</topic><topic>Feasibility Studies</topic><topic>Female</topic><topic>Heart Valve Prosthesis</topic><topic>Heart Valve Prosthesis Implantation - methods</topic><topic>Heart, Artificial</topic><topic>Humans</topic><topic>Male</topic><topic>Prostheses and Implants</topic><topic>Prosthesis Design</topic><topic>Prosthesis Failure</topic><topic>Prosthesis Fitting</topic><topic>Reoperation - methods</topic><topic>Thoracotomy - methods</topic><topic>Time Factors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kamohara, Keiji</creatorcontrib><creatorcontrib>Weber, Stephan</creatorcontrib><creatorcontrib>Klatte, Ryan S</creatorcontrib><creatorcontrib>Ootaki, Yoshio</creatorcontrib><creatorcontrib>Akiyama, Masatoshi</creatorcontrib><creatorcontrib>Kopcak, Michael W</creatorcontrib><creatorcontrib>Luangphakdy, Viviane</creatorcontrib><creatorcontrib>Flick, Christine R</creatorcontrib><creatorcontrib>Chen, Ji-Feng</creatorcontrib><creatorcontrib>Navia, Jose L</creatorcontrib><creatorcontrib>Smith, William A</creatorcontrib><creatorcontrib>Fukamachi, Kiyotaka</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>ASAIO journal (1992)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kamohara, Keiji</au><au>Weber, Stephan</au><au>Klatte, Ryan S</au><au>Ootaki, Yoshio</au><au>Akiyama, Masatoshi</au><au>Kopcak, Michael W</au><au>Luangphakdy, Viviane</au><au>Flick, Christine R</au><au>Chen, Ji-Feng</au><au>Navia, Jose L</au><au>Smith, William A</au><au>Fukamachi, Kiyotaka</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Replacement of the Left-Side Valves of an Implanted Total Artificial Heart</atitle><jtitle>ASAIO journal (1992)</jtitle><addtitle>ASAIO J</addtitle><date>2006-07</date><risdate>2006</risdate><volume>52</volume><issue>4</issue><spage>368</spage><epage>372</epage><pages>368-372</pages><issn>1058-2916</issn><eissn>1538-943X</eissn><abstract>The MagScrew total artificial heart (TAH) is under development. Despite its anticipated durability and reliability, the possibility of a bioprosthetic valve malfunction exists. As a result, the potential for valve replacement surgery, instead of device replacement, would be desirable after a TAH implant. In two of our 90-day animal experiments, we successfully replaced the left-side valves through a left thoracotomy opposite to the right-sided incision site for the initial TAH implant. The results of these cases suggest that the left-side valves could also be replaced through a left thoracotomy approach in humans. To confirm the ability to access the left-side valves in humans, four human cadaver studies were performed with the use of a mock pump designed for human application. 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subjects | Animals Bioprosthesis Cattle Feasibility Studies Female Heart Valve Prosthesis Heart Valve Prosthesis Implantation - methods Heart, Artificial Humans Male Prostheses and Implants Prosthesis Design Prosthesis Failure Prosthesis Fitting Reoperation - methods Thoracotomy - methods Time Factors |
title | Replacement of the Left-Side Valves of an Implanted Total Artificial Heart |
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