Palladium(II) and Platinum(II) Organometallic Complexes with the Model Nucleobase Anions of Thymine, Uracil, and Cytosine:  Antitumor Activity and Interactions with DNA of the Platinum Compounds

Pd(II) and Pt(II) complexes with the anions of the model nucleobases 1-methylthymine (1-MethyH), 1-methyluracil (1-MeuraH), and 1-methylcytosine (1-MecytH) of the types [Pd(dmba)(μ-L)]2 [dmba = N,C-chelating 2-((dimethylamino)methyl)phenyl; L = 1-Methy, 1-Meura or 1-Mecyt] and [M(dmba)(L)(L‘)] [L =...

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Veröffentlicht in:	Inorganic chemistry 2006-08, Vol.45 (16), p.6347-6360
Hauptverfasser:	Ruiz, José, Lorenzo, Julia, Sanglas, Laura, Cutillas, Natalia, Vicente, Consuelo, Villa, María Dolores, Avilés, Francesc X, López, Gregorio, Moreno, Virtudes, Pérez, José, Bautista, Delia
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic Agents - chemistry Antineoplastic Agents - pharmacology Cytosine - chemistry Cytosine - pharmacology DNA - metabolism HL-60 Cells Humans Organoplatinum Compounds - chemistry Organoplatinum Compounds - pharmacology Palladium - chemistry Palladium - pharmacology Thymine - chemistry Thymine - pharmacology
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