Influence of Metal Coordination on the Mismatch Tolerance of Ligand-Modified PNA Duplexes

Recent studies on metal incorporation in ligand-modified nucleic acids have focused on the effect of metal coordination on the stability of metal-containing duplexes or triplexes and on the metal binding selectivity but did not address the effect of the sequence of the nucleic acid in which the liga...

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Veröffentlicht in:	Journal of the American Chemical Society 2005-10, Vol.127 (42), p.14628-14639
Hauptverfasser:	Watson, Richard M, Skorik, Yury A, Patra, Goutam K, Achim, Catalina
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Copper - chemistry Fundamental and applied biological sciences. Psychology Interactions. Associations Intermolecular phenomena Ligands Molecular biophysics Molecular Structure Oxyquinoline - chemistry Peptide Nucleic Acids - chemical synthesis Peptide Nucleic Acids - chemistry Spectrophotometry, Ultraviolet Temperature
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