Screening for metal ligands by liquid chromatography–ligand-exchange–electrospray mass spectrometry

Electrospray ionization mass spectrometry is applied for the selective detection of metal ligands after a post-column continuous-flow ligand-exchange reaction. The detection is based on the specific release of a reporter ligand from a metal–reporter ligand complex by a high affinity ligand. Constant...

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Veröffentlicht in:	Journal of Chromatography A 2005-11, Vol.1093 (1), p.36-46
Hauptverfasser:	Krabbe, J.G., Lingeman, H., Niessen, W.M.A., Irth, H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Analytical chemistry Chemistry Chromatographic methods and physical methods associated with chromatography Chromatography, Liquid - methods Exact sciences and technology Ligand-exchange Ligands Liquid chromatography Mass spectrometry Metal ligands Metals - analysis Other chromatographic methods Screening Spectrometry, Mass, Electrospray Ionization - methods
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