Necrotizing fasciitis in neonates
Necrotizing fasciitis (NF) is a potentially life-threatening infection of soft tissues. It is characterized by rapid spread of inflammation and infection with widespread necrosis of fascia, subcutaneous tissues, and overlying skin. NF is usually reported in adults with preexisting medical conditions...
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| Veröffentlicht in: | Pediatric surgery international 2005-08, Vol.21 (8), p.641-644 |
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| description | Necrotizing fasciitis (NF) is a potentially life-threatening infection of soft tissues. It is characterized by rapid spread of inflammation and infection with widespread necrosis of fascia, subcutaneous tissues, and overlying skin. NF is usually reported in adults with preexisting medical conditions or compromised immune system. It is rare in neonates, and the reported mortality is close to 50% in this population. Less than 70 cases of neonatal NF are reported in literature, most in otherwise healthy neonates and usually attributed to omphalitis, mastitis, or postoperative wound infections. We report our experience of nine neonates who developed NF spontaneously (primary NF) and look at the etiology, clinical presentation, microbiology, management, and outcome. |
| doi_str_mv | 10.1007/s00383-005-1481-y |
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It is characterized by rapid spread of inflammation and infection with widespread necrosis of fascia, subcutaneous tissues, and overlying skin. NF is usually reported in adults with preexisting medical conditions or compromised immune system. It is rare in neonates, and the reported mortality is close to 50% in this population. Less than 70 cases of neonatal NF are reported in literature, most in otherwise healthy neonates and usually attributed to omphalitis, mastitis, or postoperative wound infections. We report our experience of nine neonates who developed NF spontaneously (primary NF) and look at the etiology, clinical presentation, microbiology, management, and outcome.</description><identifier>ISSN: 0179-0358</identifier><identifier>EISSN: 1437-9813</identifier><identifier>DOI: 10.1007/s00383-005-1481-y</identifier><identifier>PMID: 16047180</identifier><language>eng</language><publisher>Germany: Springer Nature B.V</publisher><subject>Combined Modality Therapy ; Debridement ; Fasciitis, Necrotizing - diagnosis ; Fasciitis, Necrotizing - etiology ; Fasciitis, Necrotizing - microbiology ; Fasciitis, Necrotizing - therapy ; Female ; Humans ; Infant, Newborn ; Male ; Soft Tissue Infections - diagnosis ; Soft Tissue Infections - etiology ; Soft Tissue Infections - microbiology ; Soft Tissue Infections - therapy ; Treatment Outcome</subject><ispartof>Pediatric surgery international, 2005-08, Vol.21 (8), p.641-644</ispartof><rights>Springer-Verlag 2005</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c326t-9feffb7c174a7158385b9f866f82840d628fcd8b18441a5ce82a1a1e95e8d8c23</citedby><cites>FETCH-LOGICAL-c326t-9feffb7c174a7158385b9f866f82840d628fcd8b18441a5ce82a1a1e95e8d8c23</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27903,27904</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16047180$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Nazir, Zafar</creatorcontrib><title>Necrotizing fasciitis in neonates</title><title>Pediatric surgery international</title><addtitle>Pediatr Surg Int</addtitle><description>Necrotizing fasciitis (NF) is a potentially life-threatening infection of soft tissues. It is characterized by rapid spread of inflammation and infection with widespread necrosis of fascia, subcutaneous tissues, and overlying skin. NF is usually reported in adults with preexisting medical conditions or compromised immune system. It is rare in neonates, and the reported mortality is close to 50% in this population. Less than 70 cases of neonatal NF are reported in literature, most in otherwise healthy neonates and usually attributed to omphalitis, mastitis, or postoperative wound infections. We report our experience of nine neonates who developed NF spontaneously (primary NF) and look at the etiology, clinical presentation, microbiology, management, and outcome.</description><subject>Combined Modality Therapy</subject><subject>Debridement</subject><subject>Fasciitis, Necrotizing - diagnosis</subject><subject>Fasciitis, Necrotizing - etiology</subject><subject>Fasciitis, Necrotizing - microbiology</subject><subject>Fasciitis, Necrotizing - therapy</subject><subject>Female</subject><subject>Humans</subject><subject>Infant, Newborn</subject><subject>Male</subject><subject>Soft Tissue Infections - diagnosis</subject><subject>Soft Tissue Infections - etiology</subject><subject>Soft Tissue Infections - microbiology</subject><subject>Soft Tissue Infections - therapy</subject><subject>Treatment Outcome</subject><issn>0179-0358</issn><issn>1437-9813</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2005</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNpdkD1PwzAURS0EoqXwA1hQYWAzvGc79suIKr6kChaYLcexkas2LXEylF9PqlZCYnrLuVf3HcYuEe4QwNxnAEmSAxQcFSHfHrExKml4SSiP2RjQlBxkQSN2lvMCAEjq8pSNUIMySDBm12_Bt-su_aTmaxpd9il1KU9TM23CunFdyOfsJLplDheHO2GfT48fsxc-f39-nT3MuZdCd7yMIcbKeDTKGSxIUlGVkbSOJEhBrQVFX1OFpBS6wgcSDh2GsghUkxdywm73vZt2_d2H3NlVyj4sl25Y0merSZdGCRzAm3_gYt23zbDNCiEMkDF6gHAPDd_l3IZoN21auXZrEexOnt3Ls4M8u5Nnt0Pm6lDcV6tQ_yUOtuQvYExopA</recordid><startdate>200508</startdate><enddate>200508</enddate><creator>Nazir, Zafar</creator><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9-</scope><scope>K9.</scope><scope>KB0</scope><scope>M0R</scope><scope>M0S</scope><scope>M1P</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope></search><sort><creationdate>200508</creationdate><title>Necrotizing fasciitis in neonates</title><author>Nazir, Zafar</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c326t-9feffb7c174a7158385b9f866f82840d628fcd8b18441a5ce82a1a1e95e8d8c23</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2005</creationdate><topic>Combined Modality Therapy</topic><topic>Debridement</topic><topic>Fasciitis, Necrotizing - 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It is characterized by rapid spread of inflammation and infection with widespread necrosis of fascia, subcutaneous tissues, and overlying skin. NF is usually reported in adults with preexisting medical conditions or compromised immune system. It is rare in neonates, and the reported mortality is close to 50% in this population. Less than 70 cases of neonatal NF are reported in literature, most in otherwise healthy neonates and usually attributed to omphalitis, mastitis, or postoperative wound infections. We report our experience of nine neonates who developed NF spontaneously (primary NF) and look at the etiology, clinical presentation, microbiology, management, and outcome.</abstract><cop>Germany</cop><pub>Springer Nature B.V</pub><pmid>16047180</pmid><doi>10.1007/s00383-005-1481-y</doi><tpages>4</tpages></addata></record> |
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| ispartof | Pediatric surgery international, 2005-08, Vol.21 (8), p.641-644 |
| issn | 0179-0358 1437-9813 |
| language | eng |
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| source | MEDLINE; Springer Nature - Complete Springer Journals |
| subjects | Combined Modality Therapy Debridement Fasciitis, Necrotizing - diagnosis Fasciitis, Necrotizing - etiology Fasciitis, Necrotizing - microbiology Fasciitis, Necrotizing - therapy Female Humans Infant, Newborn Male Soft Tissue Infections - diagnosis Soft Tissue Infections - etiology Soft Tissue Infections - microbiology Soft Tissue Infections - therapy Treatment Outcome |
| title | Necrotizing fasciitis in neonates |
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