Dual function of fish hepcidin: Response to experimental iron overload and bacterial infection in sea bass ( Dicentrarchus labrax)

The role of hepcidin in iron metabolism regulation and bacterial infection has been the focus of recent attention. However, in spite of the growing number of hepcidin genes known from different organisms, little is known about its putative dual function in fish. The aim of this study was to characte...

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Veröffentlicht in:	Developmental & Comparative Immunology 2006, Vol.30 (12), p.1156-1167
Hauptverfasser:	Rodrigues, Pedro N.S., Vázquez-Dorado, Sandra, Neves, João V., Wilson, Jonathan M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Antimicrobial Cationic Peptides - genetics Antimicrobial Cationic Peptides - immunology Bacteria Base Sequence Bass - immunology Bass - metabolism Dicentrarchus labrax Erythrocyte Count - veterinary Fish Diseases - genetics Fish Diseases - immunology Fish Diseases - metabolism Fish Diseases - microbiology Gene expression Gram-Negative Bacterial Infections - immunology Gram-Negative Bacterial Infections - metabolism Gram-Negative Bacterial Infections - veterinary Hematocrit - veterinary Hepcidin Hepcidins Infection Iron deficiency Iron metabolism Iron overload Iron Overload - blood Iron Overload - genetics Iron Overload - immunology Iron Overload - metabolism Liver - metabolism Molecular Sequence Data Photobacterium - growth & development Photobacterium damselae Phylogeny Reverse Transcriptase Polymerase Chain Reaction - veterinary Sea bass Sequence Alignment Transferrin - metabolism
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