Switch from inhibitory to activating NKG2 receptor expression in HIV-1 infection : lack of reversion with highly active antiretroviral therapy

HIV-1 infection is characterized by increase in inhibitory receptors and loss of activating receptors on natural killer (NK) cells, resulting in loss of cell activity. Exceptionally, for an inhibitory receptor, the proportion of NK cells bearing CD94-NKG2A decreases during HIV-1 infection. It is not...

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Veröffentlicht in:	AIDS (London) 2005-11, Vol.19 (16), p.1761-1769
Hauptverfasser:	MELA, Christopher M, BURTON, Catherine T, IMAMI, Nesrina, NELSON, Mark, STEEL, Alan, GAZZARD, Brian G, GOTCH, Frances M, GOODIER, Martin R
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibiotics. Antiinfectious agents. Antiparasitic agents Antibodies, Viral - metabolism Antiretroviral Therapy, Highly Active Antiviral agents Biological and medical sciences Cohort Studies Flow Cytometry HIV Infections - drug therapy HIV Infections - immunology HIV-1 Human immunodeficiency virus 1 Human viral diseases Humans Immunodeficiencies Immunodeficiencies. Immunoglobulinopathies Immunopathology Infectious diseases Killer Cells, Natural - metabolism Lectins, C-Type - antagonists & inhibitors Lectins, C-Type - metabolism Medical sciences Middle Aged Pharmacology. Drug treatments Viral diseases Viral diseases of the lymphoid tissue and the blood. Aids Viremia - metabolism
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