Suicidal Ideation in Multiple Sclerosis
Turner AP, Williams RM, Bowen JD, Kivlahan DR, Haselkorn JK. Suicidal ideation in multiple sclerosis. To examine risk factors for suicidal ideation among people with multiple sclerosis (MS). Cohort study linking computerized medical records with a mailed self-report survey. Veteran’s Health Administ...
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| Veröffentlicht in: | Archives of physical medicine and rehabilitation 2006-08, Vol.87 (8), p.1073-1078 |
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| creator | Turner, Aaron P. Williams, Rhonda M. Bowen, James D. Kivlahan, Daniel R. Haselkorn, Jodie K. |
| description | Turner AP, Williams RM, Bowen JD, Kivlahan DR, Haselkorn JK. Suicidal ideation in multiple sclerosis.
To examine risk factors for suicidal ideation among people with multiple sclerosis (MS).
Cohort study linking computerized medical records with a mailed self-report survey.
Veteran’s Health Administration (VHA) region covering the northwestern United States.
VHA patients with MS (N=445) who returned mailed surveys.
Not applicable.
Suicidal ideation is assessed by the Patient Health Questionnaire (PHQ) suicide item with suicidal ideation more than half the days considered persistent.
One hundred thirty-one (29.4%) of 445 respondents (95% confidence interval [CI], 25.4%–33.9%) endorsed suicidal ideation, and 35 (7.9%; 95% CI, 5.7%–10.8%) endorsed persistent suicidal ideation over the last 2 weeks. In bivariate analyses, suicidal ideation was associated with younger age, earlier disease course, progressive disease subtype, lower income, not being married, lower social support, not driving, higher levels of physical disability (mobility, bowel, bladder), and depression. Analyses on persistent suicidal ideation yielded similar results. In fully adjusted multivariate logistic regression, only depression severity and bowel disability were independently associated with suicidal ideation. Only depression severity was independently associated with persistent suicidal ideation. By using the 2-question depression screen (U.S. Preventive Services Task Force) consisting of the depression and anhedonia items from the PHQ-9, sensitivity and specificity were marginal for suicidal ideation (65.6% and 79.9%) but acceptable for persistent suicidal ideation (88.6% and 71.2%).
Suicidal ideation is common among VHA patients with MS, and depression severity is the best risk marker. Brief screening for depression in MS should include the assessment of suicidal ideation. |
| doi_str_mv | 10.1016/j.apmr.2006.04.021 |
| format | Article |
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To examine risk factors for suicidal ideation among people with multiple sclerosis (MS).
Cohort study linking computerized medical records with a mailed self-report survey.
Veteran’s Health Administration (VHA) region covering the northwestern United States.
VHA patients with MS (N=445) who returned mailed surveys.
Not applicable.
Suicidal ideation is assessed by the Patient Health Questionnaire (PHQ) suicide item with suicidal ideation more than half the days considered persistent.
One hundred thirty-one (29.4%) of 445 respondents (95% confidence interval [CI], 25.4%–33.9%) endorsed suicidal ideation, and 35 (7.9%; 95% CI, 5.7%–10.8%) endorsed persistent suicidal ideation over the last 2 weeks. In bivariate analyses, suicidal ideation was associated with younger age, earlier disease course, progressive disease subtype, lower income, not being married, lower social support, not driving, higher levels of physical disability (mobility, bowel, bladder), and depression. Analyses on persistent suicidal ideation yielded similar results. In fully adjusted multivariate logistic regression, only depression severity and bowel disability were independently associated with suicidal ideation. Only depression severity was independently associated with persistent suicidal ideation. By using the 2-question depression screen (U.S. Preventive Services Task Force) consisting of the depression and anhedonia items from the PHQ-9, sensitivity and specificity were marginal for suicidal ideation (65.6% and 79.9%) but acceptable for persistent suicidal ideation (88.6% and 71.2%).
Suicidal ideation is common among VHA patients with MS, and depression severity is the best risk marker. Brief screening for depression in MS should include the assessment of suicidal ideation.</description><identifier>ISSN: 0003-9993</identifier><identifier>EISSN: 1532-821X</identifier><identifier>DOI: 10.1016/j.apmr.2006.04.021</identifier><identifier>PMID: 16876552</identifier><identifier>CODEN: APMHAI</identifier><language>eng</language><publisher>New York, NY: Elsevier Inc</publisher><subject>Biological and medical sciences ; Chi-Square Distribution ; Depression ; Depression - epidemiology ; Depression - psychology ; Diseases of the osteoarticular system ; Human viral diseases ; Humans ; Infectious diseases ; Logistic Models ; Medical sciences ; Multiple sclerosis ; Multiple Sclerosis - epidemiology ; Multiple Sclerosis - psychology ; Multiple sclerosis and variants. Guillain barré syndrome and other inflammatory polyneuropathies. Leukoencephalitis ; Neurology ; Rehabilitation ; Risk Factors ; Sensitivity and Specificity ; Social Support ; Suicide ; Suicide - psychology ; Surveys and Questionnaires ; United States - epidemiology ; Veterans - psychology ; Viral diseases ; Viral hepatitis</subject><ispartof>Archives of physical medicine and rehabilitation, 2006-08, Vol.87 (8), p.1073-1078</ispartof><rights>2006 American Congress of Rehabilitation Medicine and the American Academy of Physical Medicine and Rehabilitation</rights><rights>2006 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c384t-3f948d4d45affc82e2d46802f4657c12202627eefd24f930617766636f99b2853</citedby><cites>FETCH-LOGICAL-c384t-3f948d4d45affc82e2d46802f4657c12202627eefd24f930617766636f99b2853</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0003999306004059$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=18027897$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16876552$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Turner, Aaron P.</creatorcontrib><creatorcontrib>Williams, Rhonda M.</creatorcontrib><creatorcontrib>Bowen, James D.</creatorcontrib><creatorcontrib>Kivlahan, Daniel R.</creatorcontrib><creatorcontrib>Haselkorn, Jodie K.</creatorcontrib><title>Suicidal Ideation in Multiple Sclerosis</title><title>Archives of physical medicine and rehabilitation</title><addtitle>Arch Phys Med Rehabil</addtitle><description>Turner AP, Williams RM, Bowen JD, Kivlahan DR, Haselkorn JK. Suicidal ideation in multiple sclerosis.
To examine risk factors for suicidal ideation among people with multiple sclerosis (MS).
Cohort study linking computerized medical records with a mailed self-report survey.
Veteran’s Health Administration (VHA) region covering the northwestern United States.
VHA patients with MS (N=445) who returned mailed surveys.
Not applicable.
Suicidal ideation is assessed by the Patient Health Questionnaire (PHQ) suicide item with suicidal ideation more than half the days considered persistent.
One hundred thirty-one (29.4%) of 445 respondents (95% confidence interval [CI], 25.4%–33.9%) endorsed suicidal ideation, and 35 (7.9%; 95% CI, 5.7%–10.8%) endorsed persistent suicidal ideation over the last 2 weeks. In bivariate analyses, suicidal ideation was associated with younger age, earlier disease course, progressive disease subtype, lower income, not being married, lower social support, not driving, higher levels of physical disability (mobility, bowel, bladder), and depression. Analyses on persistent suicidal ideation yielded similar results. In fully adjusted multivariate logistic regression, only depression severity and bowel disability were independently associated with suicidal ideation. Only depression severity was independently associated with persistent suicidal ideation. By using the 2-question depression screen (U.S. Preventive Services Task Force) consisting of the depression and anhedonia items from the PHQ-9, sensitivity and specificity were marginal for suicidal ideation (65.6% and 79.9%) but acceptable for persistent suicidal ideation (88.6% and 71.2%).
Suicidal ideation is common among VHA patients with MS, and depression severity is the best risk marker. Brief screening for depression in MS should include the assessment of suicidal ideation.</description><subject>Biological and medical sciences</subject><subject>Chi-Square Distribution</subject><subject>Depression</subject><subject>Depression - epidemiology</subject><subject>Depression - psychology</subject><subject>Diseases of the osteoarticular system</subject><subject>Human viral diseases</subject><subject>Humans</subject><subject>Infectious diseases</subject><subject>Logistic Models</subject><subject>Medical sciences</subject><subject>Multiple sclerosis</subject><subject>Multiple Sclerosis - epidemiology</subject><subject>Multiple Sclerosis - psychology</subject><subject>Multiple sclerosis and variants. Guillain barré syndrome and other inflammatory polyneuropathies. Leukoencephalitis</subject><subject>Neurology</subject><subject>Rehabilitation</subject><subject>Risk Factors</subject><subject>Sensitivity and Specificity</subject><subject>Social Support</subject><subject>Suicide</subject><subject>Suicide - psychology</subject><subject>Surveys and Questionnaires</subject><subject>United States - epidemiology</subject><subject>Veterans - psychology</subject><subject>Viral diseases</subject><subject>Viral hepatitis</subject><issn>0003-9993</issn><issn>1532-821X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2006</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kMtKAzEUhoMotl5ewIV0o65mzG0yCbiR4qVQcVEFdyFNTiBlOlOTGcG3N6WF7lwdDnz_zzkfQlcElwQTcb8qzWYdS4qxKDEvMSVHaEwqRgtJydcxGmOMWaGUYiN0ltIqr6Ji5BSNiJC1qCo6RneLIdjgTDOZOTB96NpJaCdvQ9OHTQOThW0gdimkC3TiTZPgcj_P0efz08f0tZi_v8ymj_PCMsn7gnnFpeOOV8Z7KylQx4XE1HNR1ZZQiqmgNYB3lHvFsCB1LYRgwiu1pLJi5-h217uJ3fcAqdfrkCw0jWmhG5IWUihCuMgg3YE235cieL2JYW3iryZYb_Xold7q0Vs9GnOd9eTQ9b59WK7BHSJ7Hxm42QMmWdP4aFob0oHLr9RS1Zl72HGQXfwEiDrZAK0FFyLYXrsu_HfHH3HggM0</recordid><startdate>20060801</startdate><enddate>20060801</enddate><creator>Turner, Aaron P.</creator><creator>Williams, Rhonda M.</creator><creator>Bowen, James D.</creator><creator>Kivlahan, Daniel R.</creator><creator>Haselkorn, Jodie K.</creator><general>Elsevier Inc</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20060801</creationdate><title>Suicidal Ideation in Multiple Sclerosis</title><author>Turner, Aaron P. ; Williams, Rhonda M. ; Bowen, James D. ; Kivlahan, Daniel R. ; Haselkorn, Jodie K.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c384t-3f948d4d45affc82e2d46802f4657c12202627eefd24f930617766636f99b2853</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2006</creationdate><topic>Biological and medical sciences</topic><topic>Chi-Square Distribution</topic><topic>Depression</topic><topic>Depression - epidemiology</topic><topic>Depression - psychology</topic><topic>Diseases of the osteoarticular system</topic><topic>Human viral diseases</topic><topic>Humans</topic><topic>Infectious diseases</topic><topic>Logistic Models</topic><topic>Medical sciences</topic><topic>Multiple sclerosis</topic><topic>Multiple Sclerosis - epidemiology</topic><topic>Multiple Sclerosis - psychology</topic><topic>Multiple sclerosis and variants. Guillain barré syndrome and other inflammatory polyneuropathies. Leukoencephalitis</topic><topic>Neurology</topic><topic>Rehabilitation</topic><topic>Risk Factors</topic><topic>Sensitivity and Specificity</topic><topic>Social Support</topic><topic>Suicide</topic><topic>Suicide - psychology</topic><topic>Surveys and Questionnaires</topic><topic>United States - epidemiology</topic><topic>Veterans - psychology</topic><topic>Viral diseases</topic><topic>Viral hepatitis</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Turner, Aaron P.</creatorcontrib><creatorcontrib>Williams, Rhonda M.</creatorcontrib><creatorcontrib>Bowen, James D.</creatorcontrib><creatorcontrib>Kivlahan, Daniel R.</creatorcontrib><creatorcontrib>Haselkorn, Jodie K.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Archives of physical medicine and rehabilitation</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Turner, Aaron P.</au><au>Williams, Rhonda M.</au><au>Bowen, James D.</au><au>Kivlahan, Daniel R.</au><au>Haselkorn, Jodie K.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Suicidal Ideation in Multiple Sclerosis</atitle><jtitle>Archives of physical medicine and rehabilitation</jtitle><addtitle>Arch Phys Med Rehabil</addtitle><date>2006-08-01</date><risdate>2006</risdate><volume>87</volume><issue>8</issue><spage>1073</spage><epage>1078</epage><pages>1073-1078</pages><issn>0003-9993</issn><eissn>1532-821X</eissn><coden>APMHAI</coden><abstract>Turner AP, Williams RM, Bowen JD, Kivlahan DR, Haselkorn JK. Suicidal ideation in multiple sclerosis.
To examine risk factors for suicidal ideation among people with multiple sclerosis (MS).
Cohort study linking computerized medical records with a mailed self-report survey.
Veteran’s Health Administration (VHA) region covering the northwestern United States.
VHA patients with MS (N=445) who returned mailed surveys.
Not applicable.
Suicidal ideation is assessed by the Patient Health Questionnaire (PHQ) suicide item with suicidal ideation more than half the days considered persistent.
One hundred thirty-one (29.4%) of 445 respondents (95% confidence interval [CI], 25.4%–33.9%) endorsed suicidal ideation, and 35 (7.9%; 95% CI, 5.7%–10.8%) endorsed persistent suicidal ideation over the last 2 weeks. In bivariate analyses, suicidal ideation was associated with younger age, earlier disease course, progressive disease subtype, lower income, not being married, lower social support, not driving, higher levels of physical disability (mobility, bowel, bladder), and depression. Analyses on persistent suicidal ideation yielded similar results. In fully adjusted multivariate logistic regression, only depression severity and bowel disability were independently associated with suicidal ideation. Only depression severity was independently associated with persistent suicidal ideation. By using the 2-question depression screen (U.S. Preventive Services Task Force) consisting of the depression and anhedonia items from the PHQ-9, sensitivity and specificity were marginal for suicidal ideation (65.6% and 79.9%) but acceptable for persistent suicidal ideation (88.6% and 71.2%).
Suicidal ideation is common among VHA patients with MS, and depression severity is the best risk marker. Brief screening for depression in MS should include the assessment of suicidal ideation.</abstract><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>16876552</pmid><doi>10.1016/j.apmr.2006.04.021</doi><tpages>6</tpages></addata></record> |
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| ispartof | Archives of physical medicine and rehabilitation, 2006-08, Vol.87 (8), p.1073-1078 |
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| source | MEDLINE; Elsevier ScienceDirect Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals |
| subjects | Biological and medical sciences Chi-Square Distribution Depression Depression - epidemiology Depression - psychology Diseases of the osteoarticular system Human viral diseases Humans Infectious diseases Logistic Models Medical sciences Multiple sclerosis Multiple Sclerosis - epidemiology Multiple Sclerosis - psychology Multiple sclerosis and variants. Guillain barré syndrome and other inflammatory polyneuropathies. Leukoencephalitis Neurology Rehabilitation Risk Factors Sensitivity and Specificity Social Support Suicide Suicide - psychology Surveys and Questionnaires United States - epidemiology Veterans - psychology Viral diseases Viral hepatitis |
| title | Suicidal Ideation in Multiple Sclerosis |
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