Domino paired kidney donation: a strategy to make best use of live non-directed donation
A donor and recipient who have incompatible blood groups or HLA sensitivity can be matched with another incompatible pair, to result in two compatible transplants (figure).13-19 Although there are many ways to match up a pool of incompatible pairs, the mathematical technique of optimisation helps to...
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| Veröffentlicht in: | The Lancet (British edition) 2006-07, Vol.368 (9533), p.419-421 |
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| creator | Montgomery, Robert A Gentry, Sommer E Marks, William H Warren, Daniel S Hiller, Janet Houp, Julie Zachary, Andrea A Melancon, J Keith Maley, Warren R Rabb, Hamid Simpkins, Christopher Segev, Dorry L |
| description | A donor and recipient who have incompatible blood groups or HLA sensitivity can be matched with another incompatible pair, to result in two compatible transplants (figure).13-19 Although there are many ways to match up a pool of incompatible pairs, the mathematical technique of optimisation helps to find out which matches will yield the best results.13 Nevertheless, even in paired-donation programmes in which mathematical optimisation is applied, more than 50% of the incompatible pairs in the pool remain unmatched.13,20 In many cases, pools of incompatible donor-recipient pairs have a high proportion of patients with blood types that are hard to match and those with HLA sensitisation. No funding source had a role in study design, data collection, data analysis, data interpretation, writing of the report, or the decision to submit the paper for publication. |
| doi_str_mv | 10.1016/S0140-6736(06)69115-0 |
| format | Article |
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No funding source had a role in study design, data collection, data analysis, data interpretation, writing of the report, or the decision to submit the paper for publication.</description><identifier>ISSN: 0140-6736</identifier><identifier>EISSN: 1474-547X</identifier><identifier>DOI: 10.1016/S0140-6736(06)69115-0</identifier><identifier>PMID: 16876670</identifier><identifier>CODEN: LANCAO</identifier><language>eng</language><publisher>England: Elsevier Ltd</publisher><subject>Adult ; Blood Group Incompatibility ; Data analysis ; Data collection ; Data interpretation ; Female ; Humans ; Kidney Transplantation - ethics ; Kidneys ; Living Donors - ethics ; Male ; Middle Aged ; Patients ; Resource Allocation - ethics ; Resource Allocation - methods ; Tissue and Organ Procurement - ethics ; Tissue and Organ Procurement - methods ; Transplants & implants ; Waiting Lists</subject><ispartof>The Lancet (British edition), 2006-07, Vol.368 (9533), p.419-421</ispartof><rights>2006 Elsevier Ltd</rights><rights>Copyright Lancet Ltd. Jul 29-Aug 4, 2006</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c437t-8c56543634e4afd2952e46128a9bde7ab0d36e2ba2994bbef2877cdd33ddad1e3</citedby><cites>FETCH-LOGICAL-c437t-8c56543634e4afd2952e46128a9bde7ab0d36e2ba2994bbef2877cdd33ddad1e3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0140673606691150$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65534</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16876670$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Montgomery, Robert A</creatorcontrib><creatorcontrib>Gentry, Sommer E</creatorcontrib><creatorcontrib>Marks, William H</creatorcontrib><creatorcontrib>Warren, Daniel S</creatorcontrib><creatorcontrib>Hiller, Janet</creatorcontrib><creatorcontrib>Houp, Julie</creatorcontrib><creatorcontrib>Zachary, Andrea A</creatorcontrib><creatorcontrib>Melancon, J Keith</creatorcontrib><creatorcontrib>Maley, Warren R</creatorcontrib><creatorcontrib>Rabb, Hamid</creatorcontrib><creatorcontrib>Simpkins, Christopher</creatorcontrib><creatorcontrib>Segev, Dorry L</creatorcontrib><title>Domino paired kidney donation: a strategy to make best use of live non-directed donation</title><title>The Lancet (British edition)</title><addtitle>Lancet</addtitle><description>A donor and recipient who have incompatible blood groups or HLA sensitivity can be matched with another incompatible pair, to result in two compatible transplants (figure).13-19 Although there are many ways to match up a pool of incompatible pairs, the mathematical technique of optimisation helps to find out which matches will yield the best results.13 Nevertheless, even in paired-donation programmes in which mathematical optimisation is applied, more than 50% of the incompatible pairs in the pool remain unmatched.13,20 In many cases, pools of incompatible donor-recipient pairs have a high proportion of patients with blood types that are hard to match and those with HLA sensitisation. No funding source had a role in study design, data collection, data analysis, data interpretation, writing of the report, or the decision to submit the paper for publication.</description><subject>Adult</subject><subject>Blood Group Incompatibility</subject><subject>Data analysis</subject><subject>Data collection</subject><subject>Data interpretation</subject><subject>Female</subject><subject>Humans</subject><subject>Kidney Transplantation - ethics</subject><subject>Kidneys</subject><subject>Living Donors - ethics</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Patients</subject><subject>Resource Allocation - ethics</subject><subject>Resource Allocation - methods</subject><subject>Tissue and Organ Procurement - ethics</subject><subject>Tissue and Organ Procurement - methods</subject><subject>Transplants & implants</subject><subject>Waiting 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| subjects | Adult Blood Group Incompatibility Data analysis Data collection Data interpretation Female Humans Kidney Transplantation - ethics Kidneys Living Donors - ethics Male Middle Aged Patients Resource Allocation - ethics Resource Allocation - methods Tissue and Organ Procurement - ethics Tissue and Organ Procurement - methods Transplants & implants Waiting Lists |
| title | Domino paired kidney donation: a strategy to make best use of live non-directed donation |
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