Quantification of antiretroviral drugs in dried blood spot samples by means of liquid chromatography/tandem mass spectrometry

For the first time approved antiretroviral drugs, i.e. protease inhibitors (PI) and non‐nucleoside reverse transcriptase inhibitors (NNRTI), were quantified in dried blood spots (DBS) from HIV/AIDS patient whole blood samples as the basis for therapeutic drug monitoring (TDM) by a robust simultaneou...

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Veröffentlicht in:	Rapid communications in mass spectrometry 2005-01, Vol.19 (21), p.2995-3001
Hauptverfasser:	Koal, Therese, Burhenne, Heike, Römling, Regina, Svoboda, Michal, Resch, Klaus, Kaever, Volkhard
Format:	Artikel
Sprache:	eng
Schlagworte:	Acquired Immunodeficiency Syndrome - blood Blood Specimen Collection - methods Chromatography, High Pressure Liquid - methods Drug Monitoring - methods HIV Protease Inhibitors - blood Humans Reproducibility of Results Reverse Transcriptase Inhibitors - blood Spectrometry, Mass, Electrospray Ionization - methods
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