Heterodisulfide reductase from methanogenic archaea: a new catalytic role for an iron-sulfur cluster

Heterodisulfide reductase (HDR) from methanogenic archaea is an iron-sulfur protein that catalyzes reversible reduction of the heterodisulfide (CoM-S-S-CoB) of the methanogenic thiol-coenzymes, coenzyme M (CoM-SH) and coenzyme B (CoB-SH). Via the characterization of a paramagnetic reaction intermedi...

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Veröffentlicht in:	Biological chemistry 2005-10, Vol.386 (10), p.961-970
Hauptverfasser:	Hedderich, Reiner, Hamann, Nils, Bennati, Marina
Format:	Artikel
Sprache:	eng
Schlagworte:	Archaea Binding Sites Catalysis disulfide reductase Euryarchaeota - enzymology ferredoxin:thioredoxin reductase heterodisulfide reductase iron-sulfur proteins Iron-Sulfur Proteins - chemistry Methanobacteriaceae - enzymology methanogenic archaea Methanosarcina barkeri - enzymology Oxidoreductases - chemistry Oxidoreductases - genetics Protein Subunits - chemistry Spectrum Analysis
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