Carbohydrate-Based Switch-On Molecular Sensor for Cu(II) in Buffer:  Absorption and Fluorescence Study of the Selective Recognition of Cu(II) Ions by Galactosyl Derivatives in HEPES Buffer

Carbohydrate-Based Switch-On Molecular Sensor for Cu(II) in Buffer:  Absorption and Fluorescence Study of the Selective Recognition of Cu(II) Ions by Galactosyl Derivatives in HEPES Buffer

1-(β-d-Galactopyranosyl-1‘-deoxy-1‘-iminomethyl)-2-hydroxynaphthalene (L1), possessing an ONO binding core, was found to be selective for Cu2+ ions in N-[2-hydroxyethyl]piperazine-N‘-[2-ethanesulfonic acid] buffer, at concentrations ≤580 ppb, at physiological pH by eliciting switch-on behavior, wher...

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Veröffentlicht in:Organic letters 2006-08, Vol.8 (16), p.3525-3528
Hauptverfasser: Singhal, Nitin Kumar, Ramanujam, Balaji, Mariappanadar, Vairamani, Rao, Chebrolu Pulla
Format: Artikel
Sprache:eng
Schlagworte:
Cations - chemistry
Copper - chemistry
Fluorescence
Galactose - analogs & derivatives
Galactose - chemistry
HEPES
Hydrogen-Ion Concentration
Metals - chemistry
Molecular Structure
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container_end_page 3528
container_issue 16
container_start_page 3525
container_title Organic letters
container_volume 8
creator Singhal, Nitin Kumar
Ramanujam, Balaji
Mariappanadar, Vairamani
Rao, Chebrolu Pulla
description 1-(β-d-Galactopyranosyl-1‘-deoxy-1‘-iminomethyl)-2-hydroxynaphthalene (L1), possessing an ONO binding core, was found to be selective for Cu2+ ions in N-[2-hydroxyethyl]piperazine-N‘-[2-ethanesulfonic acid] buffer, at concentrations ≤580 ppb, at physiological pH by eliciting switch-on behavior, whereas the other ions, viz., Mg2+, Ca2+, Mn2+, Fe2+, Co2+, Ni2+, Zn2+, and Cd2+, caused no significant change in the fluorescence. Whereas the binding characteristics were ascertained by absorption spectroscopy, the species formed were shown by Q-TOF ES MS.
doi_str_mv 10.1021/ol061274f
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source MEDLINE; American Chemical Society Journals
subjects Cations - chemistry
Copper - chemistry
Fluorescence
Galactose - analogs & derivatives
Galactose - chemistry
HEPES
Hydrogen-Ion Concentration
Metals - chemistry
Molecular Structure
title Carbohydrate-Based Switch-On Molecular Sensor for Cu(II) in Buffer:  Absorption and Fluorescence Study of the Selective Recognition of Cu(II) Ions by Galactosyl Derivatives in HEPES Buffer
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