Impact of vertebral artery disease on dynamic cerebral autoregulation
Objectives – This study applied dynamic cerebral autoregulation (DCA) testing distally to severe bilateral vertebral artery disease (BVAD). Methods – Using continuous monitoring of beat‐to‐beat blood pressure and transcranial Doppler of the posterior cerebral arteries (PCA) were examined in 20 pat...
Gespeichert in:
| Veröffentlicht in: | Acta neurologica Scandinavica 2005-11, Vol.112 (5), p.309-316 |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 316 |
|---|---|
| container_issue | 5 |
| container_start_page | 309 |
| container_title | Acta neurologica Scandinavica |
| container_volume | 112 |
| creator | Haubrich, C. Kohnke, A. Diehl, R. R. Möller-Hartmann, W. Klötzsch, C. |
| description | Objectives – This study applied dynamic cerebral autoregulation (DCA) testing distally to severe bilateral vertebral artery disease (BVAD).
Methods – Using continuous monitoring of beat‐to‐beat blood pressure and transcranial Doppler of the posterior cerebral arteries (PCA) were examined in 20 patients with BVAD and 22 controls. DCA testing was based on the ‘high‐pass filter model’, which predicts a positive phase relationship between spontaneous oscillations (M‐waves 3–9 cpm and R‐waves 9–20 cpm) in blood pressure and cerebral blood flow velocity.
Results – In patients with BVAD, DCA testing detected autoregulatory deficits of different degrees. The lowest M‐wave phase shift angles were found in the PCA territory distally to intracranial BVAD.
Conclusion – This study suggests that DCA testing of the PCA could help to quantify the hemodynamic impact of BVAD. It highlights the relevance of functional TCD sonography as a useful diagnostic tool for the hemodynamic evaluation of vertebrobasilar disease. |
| doi_str_mv | 10.1111/j.1600-0404.2005.00498.x |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_68680087</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>19598842</sourcerecordid><originalsourceid>FETCH-LOGICAL-c5818-37cb3ad81497c6daac85fffa821cec7503bef2b3ac9ba84c7ce549bf1cf6640c3</originalsourceid><addsrcrecordid>eNqNkE1r3DAQhkVpaDZp_0Lxpb3ZHVmyJEMvIWzTQEggbLuQixjLUvHWH1vJTnf_fbVZkxwbXTRinnc0PIQkFDIaz5dNRgVAChx4lgMUGQAvVbZ7QxbPjbdkAQA0FYzyU3IWwia-csn5O3JKRU5VSdmCLK-7LZoxGVzyaP1oK49tgrHw-6RugsVgk6FP6n2PXWMSY_2MTOPg7a-pxbEZ-vfkxGEb7If5Pic_vi1Xl9_Tm7ur68uLm9QUiqqUSVMxrBXlpTSiRjSqcM6hyqmxRhbAKuvyiJiyQsWNNLbgZeWocUJwMOycfD7O3frhz2TDqLsmGNu22NthCloooQCU_C9Iy6JUiucRVEfQ-CEEb53e-qZDv9cU9MG13uiDUn1Qqg-u9ZNrvYvRj_MfU9XZ-iU4y43ApxnAYLB1HnvThBdO0lIA55H7euT-Nq3dv3oBfXG7jEWMp8d4E0a7e46j_62FZLLQ69srzVYPq_X6571-YP8AaWCqNw</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>19598842</pqid></control><display><type>article</type><title>Impact of vertebral artery disease on dynamic cerebral autoregulation</title><source>MEDLINE</source><source>Wiley Online Library Journals Frontfile Complete</source><creator>Haubrich, C. ; Kohnke, A. ; Diehl, R. R. ; Möller-Hartmann, W. ; Klötzsch, C.</creator><creatorcontrib>Haubrich, C. ; Kohnke, A. ; Diehl, R. R. ; Möller-Hartmann, W. ; Klötzsch, C.</creatorcontrib><description>Objectives – This study applied dynamic cerebral autoregulation (DCA) testing distally to severe bilateral vertebral artery disease (BVAD).
Methods – Using continuous monitoring of beat‐to‐beat blood pressure and transcranial Doppler of the posterior cerebral arteries (PCA) were examined in 20 patients with BVAD and 22 controls. DCA testing was based on the ‘high‐pass filter model’, which predicts a positive phase relationship between spontaneous oscillations (M‐waves 3–9 cpm and R‐waves 9–20 cpm) in blood pressure and cerebral blood flow velocity.
Results – In patients with BVAD, DCA testing detected autoregulatory deficits of different degrees. The lowest M‐wave phase shift angles were found in the PCA territory distally to intracranial BVAD.
Conclusion – This study suggests that DCA testing of the PCA could help to quantify the hemodynamic impact of BVAD. It highlights the relevance of functional TCD sonography as a useful diagnostic tool for the hemodynamic evaluation of vertebrobasilar disease.</description><identifier>ISSN: 0001-6314</identifier><identifier>EISSN: 1600-0404</identifier><identifier>DOI: 10.1111/j.1600-0404.2005.00498.x</identifier><identifier>PMID: 16218913</identifier><identifier>CODEN: ANRSAS</identifier><language>eng</language><publisher>Oxford, UK: Munksgaard International Publishers</publisher><subject>Aged ; Arousal - physiology ; Attention - physiology ; Biological and medical sciences ; Blood Flow Velocity - physiology ; Blood Pressure - physiology ; Brain - blood supply ; Brain - physiopathology ; Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases ; dynamic autoregulation ; Female ; Homeostasis - physiology ; Human mycoses ; Humans ; Infectious diseases ; Male ; Medical sciences ; Middle Aged ; Mycoses ; Mycoses of the nervous system ; Neurology ; Photic Stimulation ; posterior cerebral artery ; Posterior Cerebral Artery - diagnostic imaging ; Posterior Cerebral Artery - physiopathology ; transcranial Doppler sonography ; Ultrasonography, Doppler, Transcranial ; vertebrobasilar disease ; Vertebrobasilar Insufficiency - diagnostic imaging ; Vertebrobasilar Insufficiency - physiopathology</subject><ispartof>Acta neurologica Scandinavica, 2005-11, Vol.112 (5), p.309-316</ispartof><rights>2005 INIST-CNRS</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c5818-37cb3ad81497c6daac85fffa821cec7503bef2b3ac9ba84c7ce549bf1cf6640c3</citedby><cites>FETCH-LOGICAL-c5818-37cb3ad81497c6daac85fffa821cec7503bef2b3ac9ba84c7ce549bf1cf6640c3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fj.1600-0404.2005.00498.x$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fj.1600-0404.2005.00498.x$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,777,781,1412,27905,27906,45555,45556</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=17196044$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16218913$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Haubrich, C.</creatorcontrib><creatorcontrib>Kohnke, A.</creatorcontrib><creatorcontrib>Diehl, R. R.</creatorcontrib><creatorcontrib>Möller-Hartmann, W.</creatorcontrib><creatorcontrib>Klötzsch, C.</creatorcontrib><title>Impact of vertebral artery disease on dynamic cerebral autoregulation</title><title>Acta neurologica Scandinavica</title><addtitle>Acta Neurol Scand</addtitle><description>Objectives – This study applied dynamic cerebral autoregulation (DCA) testing distally to severe bilateral vertebral artery disease (BVAD).
Methods – Using continuous monitoring of beat‐to‐beat blood pressure and transcranial Doppler of the posterior cerebral arteries (PCA) were examined in 20 patients with BVAD and 22 controls. DCA testing was based on the ‘high‐pass filter model’, which predicts a positive phase relationship between spontaneous oscillations (M‐waves 3–9 cpm and R‐waves 9–20 cpm) in blood pressure and cerebral blood flow velocity.
Results – In patients with BVAD, DCA testing detected autoregulatory deficits of different degrees. The lowest M‐wave phase shift angles were found in the PCA territory distally to intracranial BVAD.
Conclusion – This study suggests that DCA testing of the PCA could help to quantify the hemodynamic impact of BVAD. It highlights the relevance of functional TCD sonography as a useful diagnostic tool for the hemodynamic evaluation of vertebrobasilar disease.</description><subject>Aged</subject><subject>Arousal - physiology</subject><subject>Attention - physiology</subject><subject>Biological and medical sciences</subject><subject>Blood Flow Velocity - physiology</subject><subject>Blood Pressure - physiology</subject><subject>Brain - blood supply</subject><subject>Brain - physiopathology</subject><subject>Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases</subject><subject>dynamic autoregulation</subject><subject>Female</subject><subject>Homeostasis - physiology</subject><subject>Human mycoses</subject><subject>Humans</subject><subject>Infectious diseases</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Mycoses</subject><subject>Mycoses of the nervous system</subject><subject>Neurology</subject><subject>Photic Stimulation</subject><subject>posterior cerebral artery</subject><subject>Posterior Cerebral Artery - diagnostic imaging</subject><subject>Posterior Cerebral Artery - physiopathology</subject><subject>transcranial Doppler sonography</subject><subject>Ultrasonography, Doppler, Transcranial</subject><subject>vertebrobasilar disease</subject><subject>Vertebrobasilar Insufficiency - diagnostic imaging</subject><subject>Vertebrobasilar Insufficiency - physiopathology</subject><issn>0001-6314</issn><issn>1600-0404</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2005</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkE1r3DAQhkVpaDZp_0Lxpb3ZHVmyJEMvIWzTQEggbLuQixjLUvHWH1vJTnf_fbVZkxwbXTRinnc0PIQkFDIaz5dNRgVAChx4lgMUGQAvVbZ7QxbPjbdkAQA0FYzyU3IWwia-csn5O3JKRU5VSdmCLK-7LZoxGVzyaP1oK49tgrHw-6RugsVgk6FP6n2PXWMSY_2MTOPg7a-pxbEZ-vfkxGEb7If5Pic_vi1Xl9_Tm7ur68uLm9QUiqqUSVMxrBXlpTSiRjSqcM6hyqmxRhbAKuvyiJiyQsWNNLbgZeWocUJwMOycfD7O3frhz2TDqLsmGNu22NthCloooQCU_C9Iy6JUiucRVEfQ-CEEb53e-qZDv9cU9MG13uiDUn1Qqg-u9ZNrvYvRj_MfU9XZ-iU4y43ApxnAYLB1HnvThBdO0lIA55H7euT-Nq3dv3oBfXG7jEWMp8d4E0a7e46j_62FZLLQ69srzVYPq_X6571-YP8AaWCqNw</recordid><startdate>200511</startdate><enddate>200511</enddate><creator>Haubrich, C.</creator><creator>Kohnke, A.</creator><creator>Diehl, R. R.</creator><creator>Möller-Hartmann, W.</creator><creator>Klötzsch, C.</creator><general>Munksgaard International Publishers</general><general>Blackwell</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TK</scope><scope>7X8</scope></search><sort><creationdate>200511</creationdate><title>Impact of vertebral artery disease on dynamic cerebral autoregulation</title><author>Haubrich, C. ; Kohnke, A. ; Diehl, R. R. ; Möller-Hartmann, W. ; Klötzsch, C.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c5818-37cb3ad81497c6daac85fffa821cec7503bef2b3ac9ba84c7ce549bf1cf6640c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2005</creationdate><topic>Aged</topic><topic>Arousal - physiology</topic><topic>Attention - physiology</topic><topic>Biological and medical sciences</topic><topic>Blood Flow Velocity - physiology</topic><topic>Blood Pressure - physiology</topic><topic>Brain - blood supply</topic><topic>Brain - physiopathology</topic><topic>Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases</topic><topic>dynamic autoregulation</topic><topic>Female</topic><topic>Homeostasis - physiology</topic><topic>Human mycoses</topic><topic>Humans</topic><topic>Infectious diseases</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Mycoses</topic><topic>Mycoses of the nervous system</topic><topic>Neurology</topic><topic>Photic Stimulation</topic><topic>posterior cerebral artery</topic><topic>Posterior Cerebral Artery - diagnostic imaging</topic><topic>Posterior Cerebral Artery - physiopathology</topic><topic>transcranial Doppler sonography</topic><topic>Ultrasonography, Doppler, Transcranial</topic><topic>vertebrobasilar disease</topic><topic>Vertebrobasilar Insufficiency - diagnostic imaging</topic><topic>Vertebrobasilar Insufficiency - physiopathology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Haubrich, C.</creatorcontrib><creatorcontrib>Kohnke, A.</creatorcontrib><creatorcontrib>Diehl, R. R.</creatorcontrib><creatorcontrib>Möller-Hartmann, W.</creatorcontrib><creatorcontrib>Klötzsch, C.</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Neurosciences Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Acta neurologica Scandinavica</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Haubrich, C.</au><au>Kohnke, A.</au><au>Diehl, R. R.</au><au>Möller-Hartmann, W.</au><au>Klötzsch, C.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Impact of vertebral artery disease on dynamic cerebral autoregulation</atitle><jtitle>Acta neurologica Scandinavica</jtitle><addtitle>Acta Neurol Scand</addtitle><date>2005-11</date><risdate>2005</risdate><volume>112</volume><issue>5</issue><spage>309</spage><epage>316</epage><pages>309-316</pages><issn>0001-6314</issn><eissn>1600-0404</eissn><coden>ANRSAS</coden><abstract>Objectives – This study applied dynamic cerebral autoregulation (DCA) testing distally to severe bilateral vertebral artery disease (BVAD).
Methods – Using continuous monitoring of beat‐to‐beat blood pressure and transcranial Doppler of the posterior cerebral arteries (PCA) were examined in 20 patients with BVAD and 22 controls. DCA testing was based on the ‘high‐pass filter model’, which predicts a positive phase relationship between spontaneous oscillations (M‐waves 3–9 cpm and R‐waves 9–20 cpm) in blood pressure and cerebral blood flow velocity.
Results – In patients with BVAD, DCA testing detected autoregulatory deficits of different degrees. The lowest M‐wave phase shift angles were found in the PCA territory distally to intracranial BVAD.
Conclusion – This study suggests that DCA testing of the PCA could help to quantify the hemodynamic impact of BVAD. It highlights the relevance of functional TCD sonography as a useful diagnostic tool for the hemodynamic evaluation of vertebrobasilar disease.</abstract><cop>Oxford, UK</cop><pub>Munksgaard International Publishers</pub><pmid>16218913</pmid><doi>10.1111/j.1600-0404.2005.00498.x</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0001-6314 |
| ispartof | Acta neurologica Scandinavica, 2005-11, Vol.112 (5), p.309-316 |
| issn | 0001-6314 1600-0404 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_68680087 |
| source | MEDLINE; Wiley Online Library Journals Frontfile Complete |
| subjects | Aged Arousal - physiology Attention - physiology Biological and medical sciences Blood Flow Velocity - physiology Blood Pressure - physiology Brain - blood supply Brain - physiopathology Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases dynamic autoregulation Female Homeostasis - physiology Human mycoses Humans Infectious diseases Male Medical sciences Middle Aged Mycoses Mycoses of the nervous system Neurology Photic Stimulation posterior cerebral artery Posterior Cerebral Artery - diagnostic imaging Posterior Cerebral Artery - physiopathology transcranial Doppler sonography Ultrasonography, Doppler, Transcranial vertebrobasilar disease Vertebrobasilar Insufficiency - diagnostic imaging Vertebrobasilar Insufficiency - physiopathology |
| title | Impact of vertebral artery disease on dynamic cerebral autoregulation |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-20T05%3A33%3A17IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Impact%20of%20vertebral%20artery%20disease%20on%20dynamic%20cerebral%20autoregulation&rft.jtitle=Acta%20neurologica%20Scandinavica&rft.au=Haubrich,%20C.&rft.date=2005-11&rft.volume=112&rft.issue=5&rft.spage=309&rft.epage=316&rft.pages=309-316&rft.issn=0001-6314&rft.eissn=1600-0404&rft.coden=ANRSAS&rft_id=info:doi/10.1111/j.1600-0404.2005.00498.x&rft_dat=%3Cproquest_cross%3E19598842%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=19598842&rft_id=info:pmid/16218913&rfr_iscdi=true |