Hydrolysis of Acyloxy Nitroso Compounds Yields Nitroxyl (HNO)

Nitroxyl (HNO/NO-), the reduced form of nitric oxide, has gained attention based on its separate chemistry and biology from nitric oxide. The inherent reactivity of HNO requires new and mechanistically unique donors for the detailed study of HNO chemistry and biology. Oxidation of cyclohexanone oxim...

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Veröffentlicht in:	Journal of the American Chemical Society 2006-08, Vol.128 (30), p.9687-9692
Hauptverfasser:	Sha, Xin, Isbell, T. Scott, Patel, Rakesh P, Day, Cynthia S, King, S. Bruce
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Aorta - drug effects Biological and medical sciences Dose-Response Relationship, Drug Fundamental and applied biological sciences. Psychology Hydrolysis Mechanisms. Catalysis. Electron transfer. Models Models, Molecular Molecular biophysics Molecular Structure Nitrogen Oxides - chemistry Nitroso Compounds - chemistry Nitroso Compounds - pharmacology Physical chemistry in biology Rats Vasodilation - drug effects Vasodilator Agents - chemistry Vasodilator Agents - pharmacology
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