Localization of Alpha-synuclein to identified fibers and synapses in the normal mouse brain

Alpha-synuclein is a synaptic associated protein that is found throughout the brain. Although its function is not fully understood, various roles have been proposed, including the mobilization of synaptic vesicles and plasticity. However, interest in this molecule is mainly focused on its role in ne...

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Veröffentlicht in:	Neuroscience 2005, Vol.135 (3), p.907-913
Hauptverfasser:	Totterdell, S., Meredith, G.E.
Format:	Artikel
Sprache:	eng
Schlagworte:	alpha-Synuclein - metabolism Animals Biological and medical sciences Brain Chemistry - physiology Cerebral Cortex - metabolism Cerebral Cortex - ultrastructure Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases Image Processing, Computer-Assisted Immunoenzyme Techniques inclusions Medical sciences Mice Mice, Inbred C57BL Microscopy, Electron Neostriatum - metabolism Neostriatum - ultrastructure Nerve Fibers - metabolism Nerve Fibers - ultrastructure Neural Pathways - metabolism Neural Pathways - ultrastructure Neurology Parkinson Disease - pathology Parkinson’s disease Presynaptic Terminals - metabolism Substantia Nigra - metabolism Substantia Nigra - ultrastructure Synapses - metabolism Synapses - ultrastructure ultrastructure
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