Function of the vascular endothelial growth factor receptors Flt-1 and Flk-1/KDR in the alloimmune response in vivo

We have recently reported that vascular endothelial growth factor (VEGF) functions as a proinflammatory cytokine to regulate the trafficking of leukocytes into allografts in the early posttransplant period. VEGF binds two major VEGF receptors: VEGFR-1 (flt-1) and VEGFR-2 (flk-1/KDR). Here, we wished...

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Veröffentlicht in:	Transplantation 2005-09, Vol.80 (6), p.717-722
Hauptverfasser:	SHO, Masayuki, AKASHI, Satoru, YAN WU, HICKLIN, Daniel J, BRISCOE, David M, NAKAJIMA, Yoshiyuki, KANEHIRO, Hiromichi, HAMADA, Kaoru, KASHIZUKA, Hisanori, IKEDA, Naoya, NOMI, Takeo, KUZUMOTO, Yukiyasu, TSURUI, Yoshikazu, YOSHIJI, Hitoshi
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Disease Animals Biological and medical sciences Chemokines - genetics Cytokines - genetics Fundamental and applied biological sciences. Psychology Fundamental immunology Graft Rejection - immunology Immunohistochemistry Medical sciences Mice RNA, Messenger - genetics Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Tissue, organ and graft immunology Transplantation, Homologous Vascular Endothelial Growth Factor A - genetics Vascular Endothelial Growth Factor A - metabolism Vascular Endothelial Growth Factor Receptor-1 - immunology Vascular Endothelial Growth Factor Receptor-1 - metabolism
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