Effects on serotonin of (−)nicotine and dimethylphenylpiperazinium in the dorsal raphe and nucleus accumbens of freely behaving rats

The aim of this study was to investigate the neurochemical mechanism underlying the effect of nicotine and dimethylphenylpiperazinium (DMPP) on 5-hydroxytryptamine (5-HT) release in the dorsal raphe nucleus and nucleus accumbens of freely behaving rats. For comparison, lobeline, cytisine and RJR-240...

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Veröffentlicht in:	Neuroscience 2005, Vol.135 (3), p.949-958
Hauptverfasser:	Ma, Z., Strecker, R.E., McKenna, J.T., Thakkar, M.M., McCarley, R.W., Tao, R.
Format:	Artikel
Sprache:	eng
Schlagworte:	5-HT carrier 8-Hydroxy-2-(di-n-propylamino)tetralin - pharmacology addiction Animals anxiolytic Biological and medical sciences Carrier Proteins - metabolism circuitry Citalopram - pharmacology Dimethylphenylpiperazinium Iodide - pharmacology Male Medical sciences Microdialysis Neuropharmacology Nicotine - administration & dosage Nicotine - pharmacology Nicotinic Agonists - administration & dosage Nicotinic Agonists - pharmacology Nicotinic Antagonists - pharmacology nicotinic receptor Nucleus Accumbens - drug effects Nucleus Accumbens - metabolism Pharmacology. Drug treatments Psycholeptics: tranquillizer, neuroleptic Psychology. Psychoanalysis. Psychiatry Psychopharmacology Raphe Nuclei - drug effects Raphe Nuclei - metabolism Rats Rats, Sprague-Dawley Receptors, Nicotinic - drug effects Receptors, Presynaptic - drug effects Receptors, Presynaptic - metabolism Serotonin - administration & dosage Serotonin - metabolism Serotonin - pharmacology Serotonin Receptor Agonists - pharmacology serotonin reuptake transporter Serotonin Uptake Inhibitors - pharmacology
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