T-cell receptor Valpha spectratype analysis of a CD4-mediated T-cell response against minor histocompatibility antigens involved in severe graft-versus-host disease

Although CD4(+) T cells can have an important role in mediating lethal graft-versus-host disease (GVHD) directed to multiple minor histocompatibility antigens (miHA) after bone marrow transplantation, their precise characterization and effector function remains elusive. In this regard, T cell recept...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Biology of blood and marrow transplantation 2006-08, Vol.12 (8), p.818-827
Hauptverfasser:	DiRienzo, Christine G, Murphy, George F, Jones, Stephen C, Korngold, Robert, Friedman, Thea M
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals CD4-Positive T-Lymphocytes - immunology CD4-Positive T-Lymphocytes - pathology Female Gene Rearrangement, alpha-Chain T-Cell Antigen Receptor - genetics Gene Rearrangement, alpha-Chain T-Cell Antigen Receptor - immunology Graft vs Host Disease - genetics Graft vs Host Disease - immunology Graft vs Host Disease - pathology Male Mice Minor Histocompatibility Antigens - immunology Receptors, Antigen, T-Cell, alpha-beta - genetics Receptors, Antigen, T-Cell, alpha-beta - immunology Severity of Illness Index
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!