Induction of Fas clustering and apoptosis by coral prostanoid in human hormone-resistant prostate cancer cells

Cyclopentenone prostaglandins (PGs) such as PGA 1, PGA 2 and Δ 12-PGJ 2 have been shown to suppress tumor cell growth and to induce apoptosis in prostate cancer cells. Bromovulone III, which is isolated from the soft coral Clavularia viridis, is a cyclopentenone prostanoid. In this study, the anti-t...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	European journal of pharmacology 2006-08, Vol.542 (1), p.22-30
Hauptverfasser:	Chiang, Po-Cheng, Kung, Fan-Lu, Huang, Dong-Ming, Li, Tsai-Kun, Fan, Jia-Rong, Pan, Shiow-Lin, Shen, Ya-Ching, Guh, Jih-Hwa
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anthozoa - chemistry Antineoplastic Agents, Hormonal - pharmacology Apoptosis - drug effects Biological and medical sciences Blotting, Western Caspase 2 - metabolism Caspase Inhibitors Cell Cycle - drug effects Cell Line, Tumor Cell Proliferation - drug effects DNA Cleavage - drug effects DNA Fragmentation - drug effects Dose-Response Relationship, Drug Drug Resistance, Neoplasm Enzyme Activation - drug effects Fas clustering fas Receptor - metabolism Gynecology. Andrology. Obstetrics Humans Male Male genital diseases Mcl-1 cleavage Medical sciences Molecular Structure Nephrology. Urinary tract diseases Oligopeptides - pharmacology Pharmacology. Drug treatments Prostaglandin D2 - chemistry Prostaglandin D2 - pharmacology Prostaglandins - chemistry Prostaglandins - pharmacology Prostaglandins A - chemistry Prostaglandins A - pharmacology Prostanoid Prostate cancer Prostatic Neoplasms - drug therapy Prostatic Neoplasms - metabolism Prostatic Neoplasms - pathology Proto-Oncogene Proteins c-bcl-2 - metabolism Tumors Tumors of the urinary system Urinary tract. Prostate gland
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!