The Role of CXCR2/CXCR2 Ligand Biological Axis in Renal Cell Carcinoma

Renal cell carcinoma (RCC) accounts for 3% of new cancer incidence and mortality in the United States. Studies in RCC have predominantly focused on VEGF in promoting tumor-associated angiogenesis. However, other angiogenic factors may contribute to the overall angiogenic milieu of RCC. We hypothesiz...

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Veröffentlicht in:	The Journal of immunology (1950) 2005-10, Vol.175 (8), p.5351-5357
Hauptverfasser:	Mestas, Javier, Burdick, Marie D, Reckamp, Karen, Pantuck, Allan, Figlin, Robert A, Strieter, Robert M
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Carcinoma, Renal Cell - blood supply Carcinoma, Renal Cell - genetics Carcinoma, Renal Cell - metabolism Carcinoma, Renal Cell - pathology Disease Models, Animal Flow Cytometry Humans Kinetics Ligands Mice Mice, Inbred BALB C Mice, Knockout Neoplasm Metastasis - genetics Neoplasm Metastasis - immunology Neoplasm Metastasis - pathology Neovascularization, Pathologic - genetics Neovascularization, Pathologic - immunology Neovascularization, Pathologic - metabolism Receptors, Interleukin-8B - deficiency Receptors, Interleukin-8B - metabolism Receptors, Interleukin-8B - physiology Tumor Cells, Cultured
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