An Ovulatory Gonadotropin Stimulus Increases Cytosolic Phospholipase A2 Expression and Activity in Granulosa Cells of Primate Periovulatory Follicles

Context: Prostaglandins (PGs) produced within ovarian follicles in response to the ovulatory gonadotropin surge are essential for follicle rupture and oocyte release. Arachidonic acid, the common precursor for PG synthesis, is cleaved from membrane phospholipids via the activity of phospholipase A2...

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Veröffentlicht in:	The journal of clinical endocrinology and metabolism 2005-10, Vol.90 (10), p.5858-5865
Hauptverfasser:	Duffy, Diane M., Seachord, Carrie L., Dozier, Brandy L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Cells, Cultured Chorionic Gonadotropin - pharmacology Cyclooxygenase 1 Cyclooxygenase 2 Cytosol - enzymology Dinoprostone - biosynthesis Endocrinopathies Female Fundamental and applied biological sciences. Psychology Granulosa Cells - enzymology Immunohistochemistry Macaca fascicularis Medical sciences Ovarian Follicle - cytology Ovarian Follicle - enzymology Ovulation - physiology Phospholipases A - biosynthesis Phospholipases A2 Prostaglandin-Endoperoxide Synthases - biosynthesis Prostaglandins - biosynthesis Reverse Transcriptase Polymerase Chain Reaction RNA, Messenger - biosynthesis Vertebrates: endocrinology
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