Skullcapflavone I from Scutellaria baicalensis Induces Apoptosis in Activated Rat Hepatic Stellate Cells

Abstract The therapeutic goal in liver fibrosis is the reversal of fibrosis and the selective clearance by apoptosis of hepatic stellate cells (HSCs), which play a central role in liver fibrogenesis. In this study, the apoptotic effect of wogonin, oroxylin A, 2′,5,6′,7-tetrahydroxyflavone, skullcapf...

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Veröffentlicht in:	Planta medica 2005-09, Vol.71 (9), p.885-887
Hauptverfasser:	Park, Eun-Jeon, Zhao, Yu-Zhe, Lian, Lihua, Kim, Youn-Chul, Sohn, Dong Hwan
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antineoplastic Agents, Phytogenic - administration & dosage Antineoplastic Agents, Phytogenic - pharmacology Antineoplastic Agents, Phytogenic - therapeutic use Apoptosis - drug effects Caspases - metabolism Cells, Cultured Flavones - administration & dosage Flavones - pharmacology Flavones - therapeutic use Flow Cytometry Letter Liver - cytology Liver - drug effects Liver - enzymology Liver Cirrhosis - drug therapy Male Phytotherapy Plant Extracts - administration & dosage Plant Extracts - pharmacology Plant Extracts - therapeutic use Plant Roots Rats Rats, Sprague-Dawley Scutellaria baicalensis
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