Structure of the Vesicular Stomatitis Virus Nucleoprotein-RNA Complex

Vesicular stomatitis virus is a negative-stranded RNA virus. Its nucleoprotein (N) binds the viral genomic RNA and is involved in multiple functions including transcription, replication, and assembly. We have determined a 2.9 angstrom structure of a complex containing 10 molecules of the N protein a...

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Veröffentlicht in:	Science (American Association for the Advancement of Science) 2006-07, Vol.313 (5785), p.357-360
Hauptverfasser:	Green, Todd J, Zhang, Xin, Wertz, Gail W, Luo, Ming
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Biological and medical sciences Crystal structure Crystallography, X-Ray Fundamental and applied biological sciences. Psychology Hydrophobic and Hydrophilic Interactions Microbiology Models, Molecular Molecular interactions Molecular Sequence Data Molecules Monomers Morphology, structure, chemical composition, physicochemical properties Nucleic Acid Conformation Nucleocapsid Nucleocapsid Proteins - chemistry Nucleocapsid Proteins - metabolism Nucleotides Protein Conformation Protein Structure, Secondary Protein Structure, Tertiary Proteins Ribonucleic acid Ribonucleoproteins - chemistry RNA RNA, Viral - chemistry RNA, Viral - metabolism Sequence Alignment Vesicular stomatitis Indiana virus Vesicular stomatitis Indiana virus - chemistry Vesicular stomatitis virus Viral morphology Virology Viruses
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