Differential Polarization of Immune Responses by Plant 2S Seed Albumins, Ber e 1, and SFA8

The plant 2S seed albumins Ber e 1 and SFA8, although structurally very similar, vary with respect to their allergenic properties. Whereas the former represents a major allergen, the latter appears to promote only weak allergenic responses. The aim of this investigation was to determine whether the...

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Veröffentlicht in:	Journal of Immunology 2006-08, Vol.177 (3), p.1561-1566
Hauptverfasser:	Kean, Dorothy E, Goodridge, Helen S, McGuinness, Stephen, Harnett, Margaret M, Alcocer, Marcos J. C, Harnett, William
Format:	Artikel
Sprache:	eng
Schlagworte:	2S Albumins, Plant Albumins - immunology Allergens - immunology Animals Antigens, Plant Bone Marrow Cells - immunology Bone Marrow Cells - metabolism Cells, Cultured Coculture Techniques Dendritic Cells - immunology Dendritic Cells - metabolism Helianthus - immunology Lymphocyte Activation Mice Mice, Inbred BALB C Mice, Inbred C57BL Mice, Transgenic Plant Proteins - immunology Protein Precursors - immunology Resting Phase, Cell Cycle - immunology Seeds - immunology T-Lymphocytes, Helper-Inducer - cytology T-Lymphocytes, Helper-Inducer - immunology T-Lymphocytes, Helper-Inducer - metabolism
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