Nitric oxide-dependent activation of pig oocytes: Role of calcium

Pig oocytes matured in vitro are parthenogenetically activated after treatment with nitric oxide (NO)-donor SNAP. The chelation of intracellular calcium ions with BAPTA-AM suppressed the SNAP-induced activation in a dose-dependent manner. Activation by a NO-donor is dependent on the influx of calciu...

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Veröffentlicht in:	Molecular and cellular endocrinology 2005-10, Vol.242 (1), p.16-22
Hauptverfasser:	Petr, Jaroslav, Rajmon, Radko, Lánská, Vilma, Sedmíková, Markéta, Jílek, František
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Calcium Calcium - metabolism Egtazic Acid - analogs & derivatives Egtazic Acid - pharmacology Female Heparin - pharmacology Macrocyclic Compounds Nitric oxide Nitric Oxide - metabolism Oocyte Oocytes - drug effects Oocytes - metabolism Oxazoles - pharmacology Parthenogenetic activation Pig Procaine - pharmacology Ruthenium Red - pharmacology Swine Verapamil - pharmacology
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