New Developments in the Staging of Melanoma
As the incidence of melanoma increases, so does the search for new staging techniques that may provide important prognostic information and aid in the detection of early metastatic disease. The application of molecular techniques may provide powerful new tools in this search. This review summarizes...
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| Veröffentlicht in: | Cancer investigation 2005, Vol.23 (6), p.561-567 |
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| container_end_page | 567 |
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| container_title | Cancer investigation |
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| creator | Baruch, Amy C. Shi, Jiaqi Feng, Yongmei Nelson, Mark A. |
| description | As the incidence of melanoma increases, so does the search for new staging techniques that may provide important prognostic information and aid in the detection of early metastatic disease. The application of molecular techniques may provide powerful new tools in this search. This review summarizes recent findings obtained by means of conventional RT-PCR, cDNA arrays, and proteomics in the investigation of human melanoma. The molecular tools discussed in this review demonstrate how global transcript and protein analysis might contribute not only to the staging of melanoma, but may hold great promise in improving the diagnosis and treatment of this disease. |
| doi_str_mv | 10.1080/07357900500202887 |
| format | Article |
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The application of molecular techniques may provide powerful new tools in this search. This review summarizes recent findings obtained by means of conventional RT-PCR, cDNA arrays, and proteomics in the investigation of human melanoma. The molecular tools discussed in this review demonstrate how global transcript and protein analysis might contribute not only to the staging of melanoma, but may hold great promise in improving the diagnosis and treatment of this disease.</description><identifier>ISSN: 0735-7907</identifier><identifier>EISSN: 1532-4192</identifier><identifier>DOI: 10.1080/07357900500202887</identifier><identifier>PMID: 16203664</identifier><language>eng</language><publisher>England: Informa UK Ltd</publisher><subject>Biomarkers, Tumor - analysis ; cDNA arrays ; Humans ; Melanoma ; Melanoma - genetics ; Melanoma - pathology ; Molecular techniques ; Neoplasm Staging ; Oligonucleotide Array Sequence Analysis ; Proteomics ; Reverse Transcriptase Polymerase Chain Reaction ; RT-PCR ; Skin Neoplasms - genetics ; Skin Neoplasms - pathology ; Staging</subject><ispartof>Cancer investigation, 2005, Vol.23 (6), p.561-567</ispartof><rights>2005 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted 2005</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c404t-244a36399bbdc505d19942683d6d7e41196d53fda618de2bef53367f95c7a8533</citedby><cites>FETCH-LOGICAL-c404t-244a36399bbdc505d19942683d6d7e41196d53fda618de2bef53367f95c7a8533</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.tandfonline.com/doi/pdf/10.1080/07357900500202887$$EPDF$$P50$$Ginformaworld$$H</linktopdf><linktohtml>$$Uhttps://www.tandfonline.com/doi/full/10.1080/07357900500202887$$EHTML$$P50$$Ginformaworld$$H</linktohtml><link.rule.ids>314,780,784,4024,27923,27924,27925,59647,59753,60436,60542,61221,61256,61402,61437</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16203664$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Baruch, Amy C.</creatorcontrib><creatorcontrib>Shi, Jiaqi</creatorcontrib><creatorcontrib>Feng, Yongmei</creatorcontrib><creatorcontrib>Nelson, Mark A.</creatorcontrib><title>New Developments in the Staging of Melanoma</title><title>Cancer investigation</title><addtitle>Cancer Invest</addtitle><description>As the incidence of melanoma increases, so does the search for new staging techniques that may provide important prognostic information and aid in the detection of early metastatic disease. The application of molecular techniques may provide powerful new tools in this search. This review summarizes recent findings obtained by means of conventional RT-PCR, cDNA arrays, and proteomics in the investigation of human melanoma. The molecular tools discussed in this review demonstrate how global transcript and protein analysis might contribute not only to the staging of melanoma, but may hold great promise in improving the diagnosis and treatment of this disease.</description><subject>Biomarkers, Tumor - analysis</subject><subject>cDNA arrays</subject><subject>Humans</subject><subject>Melanoma</subject><subject>Melanoma - genetics</subject><subject>Melanoma - pathology</subject><subject>Molecular techniques</subject><subject>Neoplasm Staging</subject><subject>Oligonucleotide Array Sequence Analysis</subject><subject>Proteomics</subject><subject>Reverse Transcriptase Polymerase Chain Reaction</subject><subject>RT-PCR</subject><subject>Skin Neoplasms - genetics</subject><subject>Skin Neoplasms - pathology</subject><subject>Staging</subject><issn>0735-7907</issn><issn>1532-4192</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2005</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kE1Lw0AQhhdRbK3-AC-SkxeJ7nc26EXqJ1Q9qOdlk520KUm27iaW_ntTWhARepqBed6X4UHolOBLghW-wgkTSYqxwJhiqlSyh4ZEMBpzktJ9NFzf4x5IBugohDnGRNFEHKIBkRQzKfkQXbzCMrqDb6jcooamDVHZRO0MovfWTMtmGrkieoHKNK42x-igMFWAk-0coc-H-4_xUzx5e3we307inGPexpRzwyRL0yyzucDCkjTlVCpmpU2AE5JKK1hhjSTKAs2gEIzJpEhFnhjV7yN0vuldePfVQWh1XYYcqv4LcF3QUsmeUrwHyQbMvQvBQ6EXvqyNX2mC9dqQ_meoz5xty7usBvub2CrpgZsNUDaF87VZOl9Z3ZpV5XzhTZOXQbNd_dd_4jMwVTvLjQc9d51venE7vvsBBD2Dkw</recordid><startdate>2005</startdate><enddate>2005</enddate><creator>Baruch, Amy C.</creator><creator>Shi, Jiaqi</creator><creator>Feng, Yongmei</creator><creator>Nelson, Mark A.</creator><general>Informa UK Ltd</general><general>Taylor & Francis</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>2005</creationdate><title>New Developments in the Staging of Melanoma</title><author>Baruch, Amy C. ; Shi, Jiaqi ; Feng, Yongmei ; Nelson, Mark A.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c404t-244a36399bbdc505d19942683d6d7e41196d53fda618de2bef53367f95c7a8533</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2005</creationdate><topic>Biomarkers, Tumor - analysis</topic><topic>cDNA arrays</topic><topic>Humans</topic><topic>Melanoma</topic><topic>Melanoma - genetics</topic><topic>Melanoma - pathology</topic><topic>Molecular techniques</topic><topic>Neoplasm Staging</topic><topic>Oligonucleotide Array Sequence Analysis</topic><topic>Proteomics</topic><topic>Reverse Transcriptase Polymerase Chain Reaction</topic><topic>RT-PCR</topic><topic>Skin Neoplasms - genetics</topic><topic>Skin Neoplasms - pathology</topic><topic>Staging</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Baruch, Amy C.</creatorcontrib><creatorcontrib>Shi, Jiaqi</creatorcontrib><creatorcontrib>Feng, Yongmei</creatorcontrib><creatorcontrib>Nelson, Mark A.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Cancer investigation</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Baruch, Amy C.</au><au>Shi, Jiaqi</au><au>Feng, Yongmei</au><au>Nelson, Mark A.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>New Developments in the Staging of Melanoma</atitle><jtitle>Cancer investigation</jtitle><addtitle>Cancer Invest</addtitle><date>2005</date><risdate>2005</risdate><volume>23</volume><issue>6</issue><spage>561</spage><epage>567</epage><pages>561-567</pages><issn>0735-7907</issn><eissn>1532-4192</eissn><abstract>As the incidence of melanoma increases, so does the search for new staging techniques that may provide important prognostic information and aid in the detection of early metastatic disease. 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| fulltext | fulltext |
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| ispartof | Cancer investigation, 2005, Vol.23 (6), p.561-567 |
| issn | 0735-7907 1532-4192 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_68653384 |
| source | MEDLINE; Taylor & Francis:Master (3349 titles); Taylor & Francis Medical Library - CRKN |
| subjects | Biomarkers, Tumor - analysis cDNA arrays Humans Melanoma Melanoma - genetics Melanoma - pathology Molecular techniques Neoplasm Staging Oligonucleotide Array Sequence Analysis Proteomics Reverse Transcriptase Polymerase Chain Reaction RT-PCR Skin Neoplasms - genetics Skin Neoplasms - pathology Staging |
| title | New Developments in the Staging of Melanoma |
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