Long-term GnRH agonist treatment for female central precocious puberty does not impair reproductive function

Depot gonadotropin releasing hormone (GnRH) agonist (GnRHa) therapy is the treatment of choice for patients with central precocious puberty (CPP). It is still unclear whether long-term exposure to GnRHa is associated with impaired reproductive function in adulthood. The present study was performed o...

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Veröffentlicht in:	Molecular and cellular endocrinology 2006-07, Vol.254, p.217-220
Hauptverfasser:	Heger, Sabine, Müller, Marina, Ranke, Michael, Schwarz, Hans-Peter, Waldhauser, Franz, Partsch, Carl-Joachim, Sippell, Wolfgang G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Androgens - adverse effects Body Height - drug effects Body Mass Index Body Weight - drug effects Central precocious puberty Delayed-Action Preparations - administration & dosage Depot GnRH agonist Drug Administration Routes Female Fertility - drug effects Follow-Up Studies Genital Diseases, Female - etiology Gonadotropin-Releasing Hormone - administration & dosage Gonadotropin-Releasing Hormone - agonists Gonadotropin-Releasing Hormone - therapeutic use Health Status Humans Hyperandrogenism Hyperandrogenism - diagnosis Interviews as Topic Long-Term Care Menstrual Cycle - drug effects Puberty, Precocious - complications Puberty, Precocious - drug therapy Reproduction - drug effects Reproductive function Triptorelin Pamoate - therapeutic use
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