Activation, cytokine production, and intracellular survival of bacteria in Salmonella-infected human monocyte-derived macrophages and dendritic cells

Salmonella enterica serovar typhimurium (S. typhimurium) is an intracellular pathogen causing localized gastroenteritis in humans. Macrophages (Mφs) and dendritic cells (DCs) play an important role in innate immunity against Salmonella. In this report, we have compared the consequences of infection...

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Veröffentlicht in:	Journal of leukocyte biology 2005-10, Vol.78 (4), p.909-920
Hauptverfasser:	Pietilä, Taija E, Veckman, Ville, Kyllönen, Päivi, Lähteenmäki, Kaarina, Korhonen, Timo K, Julkunen, Ilkka
Format:	Artikel
Sprache:	eng
Schlagworte:	Antigens, Surface - genetics Antigens, Surface - metabolism Bacterial Proteins - metabolism Cell Differentiation - immunology Cells, Cultured Chemokines - biosynthesis Chemokines - genetics Cytokines - biosynthesis Cytokines - genetics Dendritic Cells - immunology Dendritic Cells - metabolism Dendritic Cells - microbiology Endopeptidases - metabolism Humans IFN‐γ innate immunity Interferon-gamma - biosynthesis Interferon-gamma - metabolism Macrophage Activation - immunology Macrophages - immunology Macrophages - metabolism Macrophages - microbiology Monocytes - immunology Monocytes - metabolism PgtE RNA, Messenger - genetics RNA, Messenger - metabolism Salmonella enterica Salmonella Infections - immunology Salmonella typhimurium Salmonella typhimurium - physiology Time Factors
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