Aldosterone Stimulates Collagen Gene Expression and Synthesis Via Activation of ERK1/2 in Rat Renal Fibroblasts

Recently, we demonstrated that in rats treated chronically with aldosterone and salt, severe tubulointerstitial fibrosis is associated with the activation of mitogen-activated protein kinases (MAPKs), including extracellular signal-regulated kinases (ERK1/2). Here, we investigated whether aldosteron...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Hypertension (Dallas, Tex. 1979) Tex. 1979), 2005-10, Vol.46 (4, Part 2 Suppl), p.1039-1045
Hauptverfasser:	Nagai, Yukiko, Miyata, Kayoko, Sun, Guang-Ping, Rahman, Matlubur, Kimura, Shoji, Miyatake, Akira, Kiyomoto, Hideyasu, Kohno, Masakazu, Abe, Youichi, Yoshizumi, Masanori, Nishiyama, Akira
Format:	Artikel
Sprache:	eng
Schlagworte:	Aldosterone - pharmacology Animals Blotting, Western Cells, Cultured Collagen - biosynthesis Collagen - genetics Computer Systems Enzyme Activation Extracellular Signal-Regulated MAP Kinases - metabolism Fibroblasts - metabolism Gene Expression - drug effects Kidney - cytology Mitogen-Activated Protein Kinase 1 - metabolism Mitogen-Activated Protein Kinase 3 - metabolism Phosphorylation - drug effects Polymerase Chain Reaction Rats Receptors, Mineralocorticoid - metabolism RNA, Messenger - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!