Synthesis of 13-amino costunolide derivatives as anticancer agents

A number of 13-amino costunolide derivatives ( 4a– p) have synthesized and several of them have shown better cytotoxicity with better safety index as compared to costunolide. A number of costunolide derivatives ( 4a– p) have been synthesized and evaluated for their in vitro cytotoxicity against eigh...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Bioorganic & medicinal chemistry letters 2006-08, Vol.16 (16), p.4195-4199
Hauptverfasser:	Srivastava, Sanjay K., Abraham, Aji, Bhat, Beena, Jaggi, Manu, Singh, Anu T., Sanna, Vinod K., Singh, Gurvinder, Agarwal, Shiv K., Mukherjee, Rama, Burman, Anand C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anticancer Antineoplastic agents Antineoplastic Agents - chemical synthesis Antineoplastic Agents - pharmacology Biological and medical sciences Cell Line Cell Line, Tumor Chemistry, Pharmaceutical - methods Costunolide derivatives Drug Design Drug Screening Assays, Antitumor General aspects Humans K562 Cells Medical sciences Mice Models, Chemical Pharmacology. Drug treatments Sesquiterpenes - chemical synthesis Sesquiterpenes - chemistry
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!