Neurons in the guinea pig ( Cavia porcellus) lateral lumbosacral spinal cord project to the central part of the lateral periaqueductal gray matter
In order to micturate successfully, information from the bladder has to be conveyed to the brainstem. In most experimental animals, this information is relayed, via the lumbosacral spinal cord, to the periaqueductal gray matter (PAG). Although the rat is the most used experimental animal in neurouro...
Gespeichert in:
| Veröffentlicht in: | Brain research 2006-07, Vol.1101 (1), p.43-50 |
|---|---|
| Hauptverfasser: | , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 50 |
|---|---|
| container_issue | 1 |
| container_start_page | 43 |
| container_title | Brain research |
| container_volume | 1101 |
| creator | Kuipers, Rutger Klop, Esther Marije |
| description | In order to micturate successfully, information from the bladder has to be conveyed to the brainstem. In most experimental animals, this information is relayed, via the lumbosacral spinal cord, to the periaqueductal gray matter (PAG). Although the rat is the most used experimental animal in neurourological research, urodynamic studies show that guinea pig may be a better small experimental animal because its urodynamic profile is, in contrast to that of a rat, similar to that of humans. Therefore, the present study, using anterograde and retrograde tracing, was performed to determine whether the lumbosacral spinal cord projects to the PAG in guinea pig. Results show that neurons in the lateral part of the lumbosacral spinal cord project to the central parts of the PAG. This pathway may convey information about the level of bladder filling to the PAG. |
| doi_str_mv | 10.1016/j.brainres.2006.05.039 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_68640735</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0006899306013874</els_id><sourcerecordid>68640735</sourcerecordid><originalsourceid>FETCH-LOGICAL-c427t-de6889795abfbd994ae94b38dc549061476fe6966c1b6b7a0d30b5dd1a69d4b63</originalsourceid><addsrcrecordid>eNqFkU1v1DAQhi0EokvhL1S-gOCQYOfDiW9UK76kCi5wtsb2ZPEqiYPtVOrf4BfjdLfqsacZe54Zv56XkCvOSs64-HgsdQA3B4xlxZgoWVuyWj4jO953VSGqhj0nO5YrRS9lfUFexXjMx7qW7CW54KLrK9bVO_LvB67Bz5G6maY_SA-rmxHo4g70Pd3Drcu5DwbHcY0f6AgJA4x0XCftI5gtj4ubczA-WLoEf0STaPL3wwzOaUMWCIn64f7uYcSCwcHfFe1qUj4eAtzRCVIuviYvBhgjvjnHS_L7y-df-2_Fzc-v3_fXN4Vpqi4VFkXfy062oAdtpWwAZaPr3pq2kUzwphMDCimE4VroDpitmW6t5SCkbbSoL8m709ysOguJSU0ubj-FGf0alehFk3fUPglyWcm2EzKD4gSa4GMMOKgluAnCneJMbbapo3qwTW22KdaqbFtuvDq_sOoJ7WPb2acMvD0DEA2MQ4DZuPjIdVJwITapn04c5sXdOgwqGoezQetCNkZZ757S8h-GTrwh</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>19295769</pqid></control><display><type>article</type><title>Neurons in the guinea pig ( Cavia porcellus) lateral lumbosacral spinal cord project to the central part of the lateral periaqueductal gray matter</title><source>MEDLINE</source><source>Elsevier ScienceDirect Journals</source><creator>Kuipers, Rutger ; Klop, Esther Marije</creator><creatorcontrib>Kuipers, Rutger ; Klop, Esther Marije</creatorcontrib><description>In order to micturate successfully, information from the bladder has to be conveyed to the brainstem. In most experimental animals, this information is relayed, via the lumbosacral spinal cord, to the periaqueductal gray matter (PAG). Although the rat is the most used experimental animal in neurourological research, urodynamic studies show that guinea pig may be a better small experimental animal because its urodynamic profile is, in contrast to that of a rat, similar to that of humans. Therefore, the present study, using anterograde and retrograde tracing, was performed to determine whether the lumbosacral spinal cord projects to the PAG in guinea pig. Results show that neurons in the lateral part of the lumbosacral spinal cord project to the central parts of the PAG. This pathway may convey information about the level of bladder filling to the PAG.</description><identifier>ISSN: 0006-8993</identifier><identifier>EISSN: 1872-6240</identifier><identifier>DOI: 10.1016/j.brainres.2006.05.039</identifier><identifier>PMID: 16782073</identifier><identifier>CODEN: BRREAP</identifier><language>eng</language><publisher>London: Elsevier B.V</publisher><subject>Anatomy ; Animals ; Biological and medical sciences ; Bladder ; Brain Mapping ; Cavia porcellus ; Central nervous system ; Fundamental and applied biological sciences. Psychology ; Guinea Pigs ; Limbic system ; Lumbosacral Region ; Micturition ; Neural Pathways - anatomy & histology ; Neurons - physiology ; Periaqueductal Gray - anatomy & histology ; Periaqueductal Gray - metabolism ; Spinal Cord - cytology ; Spinomesencephalic ; Vertebrates: nervous system and sense organs ; Visceroception ; Wheat Germ Agglutinin-Horseradish Peroxidase Conjugate - pharmacokinetics</subject><ispartof>Brain research, 2006-07, Vol.1101 (1), p.43-50</ispartof><rights>2006 Elsevier B.V.</rights><rights>2006 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c427t-de6889795abfbd994ae94b38dc549061476fe6966c1b6b7a0d30b5dd1a69d4b63</citedby><cites>FETCH-LOGICAL-c427t-de6889795abfbd994ae94b38dc549061476fe6966c1b6b7a0d30b5dd1a69d4b63</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0006899306013874$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=17961665$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16782073$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Kuipers, Rutger</creatorcontrib><creatorcontrib>Klop, Esther Marije</creatorcontrib><title>Neurons in the guinea pig ( Cavia porcellus) lateral lumbosacral spinal cord project to the central part of the lateral periaqueductal gray matter</title><title>Brain research</title><addtitle>Brain Res</addtitle><description>In order to micturate successfully, information from the bladder has to be conveyed to the brainstem. In most experimental animals, this information is relayed, via the lumbosacral spinal cord, to the periaqueductal gray matter (PAG). Although the rat is the most used experimental animal in neurourological research, urodynamic studies show that guinea pig may be a better small experimental animal because its urodynamic profile is, in contrast to that of a rat, similar to that of humans. Therefore, the present study, using anterograde and retrograde tracing, was performed to determine whether the lumbosacral spinal cord projects to the PAG in guinea pig. Results show that neurons in the lateral part of the lumbosacral spinal cord project to the central parts of the PAG. This pathway may convey information about the level of bladder filling to the PAG.</description><subject>Anatomy</subject><subject>Animals</subject><subject>Biological and medical sciences</subject><subject>Bladder</subject><subject>Brain Mapping</subject><subject>Cavia porcellus</subject><subject>Central nervous system</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Guinea Pigs</subject><subject>Limbic system</subject><subject>Lumbosacral Region</subject><subject>Micturition</subject><subject>Neural Pathways - anatomy & histology</subject><subject>Neurons - physiology</subject><subject>Periaqueductal Gray - anatomy & histology</subject><subject>Periaqueductal Gray - metabolism</subject><subject>Spinal Cord - cytology</subject><subject>Spinomesencephalic</subject><subject>Vertebrates: nervous system and sense organs</subject><subject>Visceroception</subject><subject>Wheat Germ Agglutinin-Horseradish Peroxidase Conjugate - pharmacokinetics</subject><issn>0006-8993</issn><issn>1872-6240</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2006</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkU1v1DAQhi0EokvhL1S-gOCQYOfDiW9UK76kCi5wtsb2ZPEqiYPtVOrf4BfjdLfqsacZe54Zv56XkCvOSs64-HgsdQA3B4xlxZgoWVuyWj4jO953VSGqhj0nO5YrRS9lfUFexXjMx7qW7CW54KLrK9bVO_LvB67Bz5G6maY_SA-rmxHo4g70Pd3Drcu5DwbHcY0f6AgJA4x0XCftI5gtj4ubczA-WLoEf0STaPL3wwzOaUMWCIn64f7uYcSCwcHfFe1qUj4eAtzRCVIuviYvBhgjvjnHS_L7y-df-2_Fzc-v3_fXN4Vpqi4VFkXfy062oAdtpWwAZaPr3pq2kUzwphMDCimE4VroDpitmW6t5SCkbbSoL8m709ysOguJSU0ubj-FGf0alehFk3fUPglyWcm2EzKD4gSa4GMMOKgluAnCneJMbbapo3qwTW22KdaqbFtuvDq_sOoJ7WPb2acMvD0DEA2MQ4DZuPjIdVJwITapn04c5sXdOgwqGoezQetCNkZZ757S8h-GTrwh</recordid><startdate>20060726</startdate><enddate>20060726</enddate><creator>Kuipers, Rutger</creator><creator>Klop, Esther Marije</creator><general>Elsevier B.V</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TK</scope><scope>7X8</scope></search><sort><creationdate>20060726</creationdate><title>Neurons in the guinea pig ( Cavia porcellus) lateral lumbosacral spinal cord project to the central part of the lateral periaqueductal gray matter</title><author>Kuipers, Rutger ; Klop, Esther Marije</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c427t-de6889795abfbd994ae94b38dc549061476fe6966c1b6b7a0d30b5dd1a69d4b63</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2006</creationdate><topic>Anatomy</topic><topic>Animals</topic><topic>Biological and medical sciences</topic><topic>Bladder</topic><topic>Brain Mapping</topic><topic>Cavia porcellus</topic><topic>Central nervous system</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Guinea Pigs</topic><topic>Limbic system</topic><topic>Lumbosacral Region</topic><topic>Micturition</topic><topic>Neural Pathways - anatomy & histology</topic><topic>Neurons - physiology</topic><topic>Periaqueductal Gray - anatomy & histology</topic><topic>Periaqueductal Gray - metabolism</topic><topic>Spinal Cord - cytology</topic><topic>Spinomesencephalic</topic><topic>Vertebrates: nervous system and sense organs</topic><topic>Visceroception</topic><topic>Wheat Germ Agglutinin-Horseradish Peroxidase Conjugate - pharmacokinetics</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kuipers, Rutger</creatorcontrib><creatorcontrib>Klop, Esther Marije</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Neurosciences Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Brain research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kuipers, Rutger</au><au>Klop, Esther Marije</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Neurons in the guinea pig ( Cavia porcellus) lateral lumbosacral spinal cord project to the central part of the lateral periaqueductal gray matter</atitle><jtitle>Brain research</jtitle><addtitle>Brain Res</addtitle><date>2006-07-26</date><risdate>2006</risdate><volume>1101</volume><issue>1</issue><spage>43</spage><epage>50</epage><pages>43-50</pages><issn>0006-8993</issn><eissn>1872-6240</eissn><coden>BRREAP</coden><abstract>In order to micturate successfully, information from the bladder has to be conveyed to the brainstem. In most experimental animals, this information is relayed, via the lumbosacral spinal cord, to the periaqueductal gray matter (PAG). Although the rat is the most used experimental animal in neurourological research, urodynamic studies show that guinea pig may be a better small experimental animal because its urodynamic profile is, in contrast to that of a rat, similar to that of humans. Therefore, the present study, using anterograde and retrograde tracing, was performed to determine whether the lumbosacral spinal cord projects to the PAG in guinea pig. Results show that neurons in the lateral part of the lumbosacral spinal cord project to the central parts of the PAG. This pathway may convey information about the level of bladder filling to the PAG.</abstract><cop>London</cop><cop>Amsterdam</cop><cop>New York, NY</cop><pub>Elsevier B.V</pub><pmid>16782073</pmid><doi>10.1016/j.brainres.2006.05.039</doi><tpages>8</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0006-8993 |
| ispartof | Brain research, 2006-07, Vol.1101 (1), p.43-50 |
| issn | 0006-8993 1872-6240 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_68640735 |
| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Anatomy Animals Biological and medical sciences Bladder Brain Mapping Cavia porcellus Central nervous system Fundamental and applied biological sciences. Psychology Guinea Pigs Limbic system Lumbosacral Region Micturition Neural Pathways - anatomy & histology Neurons - physiology Periaqueductal Gray - anatomy & histology Periaqueductal Gray - metabolism Spinal Cord - cytology Spinomesencephalic Vertebrates: nervous system and sense organs Visceroception Wheat Germ Agglutinin-Horseradish Peroxidase Conjugate - pharmacokinetics |
| title | Neurons in the guinea pig ( Cavia porcellus) lateral lumbosacral spinal cord project to the central part of the lateral periaqueductal gray matter |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-01T16%3A16%3A01IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Neurons%20in%20the%20guinea%20pig%20(%20Cavia%20porcellus)%20lateral%20lumbosacral%20spinal%20cord%20project%20to%20the%20central%20part%20of%20the%20lateral%20periaqueductal%20gray%20matter&rft.jtitle=Brain%20research&rft.au=Kuipers,%20Rutger&rft.date=2006-07-26&rft.volume=1101&rft.issue=1&rft.spage=43&rft.epage=50&rft.pages=43-50&rft.issn=0006-8993&rft.eissn=1872-6240&rft.coden=BRREAP&rft_id=info:doi/10.1016/j.brainres.2006.05.039&rft_dat=%3Cproquest_cross%3E68640735%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=19295769&rft_id=info:pmid/16782073&rft_els_id=S0006899306013874&rfr_iscdi=true |