beta1-Integrins determine the dendritic morphology which enhances DC-SIGN-mediated particle capture by dendritic cells

The morphology of antigen-presenting dendritic cells (DCs) is characterized by the presence of numerous long dendrites. The formation of these processes is shown to require the interaction between the beta1-integrin (CD29) on the surface of the DCs and fibronectin in the extracellular matrix. This i...

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Veröffentlicht in:	International immunology 2006-08, Vol.18 (8), p.1295-1303
Hauptverfasser:	Swetman Andersen, Claire A, Handley, Matthew, Pollara, Gabriel, Ridley, Anne J, Katz, David R, Chain, Benjamin M
Format:	Artikel
Sprache:	eng
Schlagworte:	Actins - metabolism Cell Adhesion Molecules - immunology Cell Adhesion Molecules - metabolism Cell Movement - immunology Cytoskeleton - metabolism Dendritic Cells - cytology Dendritic Cells - immunology Dendritic Cells - metabolism Fibronectins - metabolism Humans Integrin beta1 - immunology Lectins, C-Type - immunology Lectins, C-Type - metabolism Microtubules - metabolism Receptors, Cell Surface - immunology Receptors, Cell Surface - metabolism
Online-Zugang:	Volltext
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