IL-18 produced by thymic epithelial cells induces development of dendritic cells with CD11b in the fetal thymus

Thymic dendritic cells (DCs) are suggested to be involved in T cell selection; however, their exact origin and function remain to be established. Although DCs in the adult thymus are mostly CD8α+CD11b−, we found that CD8α−CD11b+ DCs were abundantly present in the fetal thymus and they possessed anti...

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