Sudden unexplained death in children with epilepsy : A cohort study with an eighteen-year follow-up
Sudden unexplained death is a significant cause of mortality in adults with epilepsy. Only a few data exist about this risk in childhood. Cases of sudden unexplained death in epilepsy (SUDEP) up to the age of 18 y occurring at our hospital between 1984 and 2001 were identified. The incidence rate wa...
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| Veröffentlicht in: | Acta pædiatrica (Oslo) 2005-05, Vol.94 (5), p.564-567 |
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| container_title | Acta pædiatrica (Oslo) |
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| creator | WEBER, Peter BUBL, Reinhard BLAUENSTEIN, Ursula TILLMANN, Bettina U LÜTSCHG, Jürg |
| description | Sudden unexplained death is a significant cause of mortality in adults with epilepsy. Only a few data exist about this risk in childhood.
Cases of sudden unexplained death in epilepsy (SUDEP) up to the age of 18 y occurring at our hospital between 1984 and 2001 were identified. The incidence rate was calculated on the basis of diagnosed epileptics registered with a statutory disability insurance scheme.
Four cases of SUDEP were identified during the 18-y period. The incidence of SUDEP was 4.3 per 10,000 patient-years. All children showed polytherapy-refractory epilepsy, developmental retardation and early-onset epilepsy. Two witnessed cases had shown no previous signs of seizure.
SUDEP is rare in childhood. Children with uncomplicated epilepsy seem not to be at risk. |
| doi_str_mv | 10.1080/08035250410023872 |
| format | Article |
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Cases of sudden unexplained death in epilepsy (SUDEP) up to the age of 18 y occurring at our hospital between 1984 and 2001 were identified. The incidence rate was calculated on the basis of diagnosed epileptics registered with a statutory disability insurance scheme.
Four cases of SUDEP were identified during the 18-y period. The incidence of SUDEP was 4.3 per 10,000 patient-years. All children showed polytherapy-refractory epilepsy, developmental retardation and early-onset epilepsy. Two witnessed cases had shown no previous signs of seizure.
SUDEP is rare in childhood. Children with uncomplicated epilepsy seem not to be at risk.</description><identifier>ISSN: 0803-5253</identifier><identifier>EISSN: 1651-2227</identifier><identifier>DOI: 10.1080/08035250410023872</identifier><identifier>PMID: 16188745</identifier><language>eng</language><publisher>Oxford: Blackwell</publisher><subject>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy ; Anticonvulsants - therapeutic use ; Biological and medical sciences ; Child ; Child, Preschool ; Cohort Studies ; Death, Sudden - epidemiology ; Developmental Disabilities - complications ; Emergency and intensive care: neonates and children. Prematurity. Sudden death ; Epilepsy - complications ; Epilepsy - drug therapy ; Epilepsy - epidemiology ; Female ; General aspects ; Headache. Facial pains. Syncopes. Epilepsia. Intracranial hypertension. Brain oedema. Cerebral palsy ; Humans ; Incidence ; Infant ; Intensive care medicine ; Male ; Medical sciences ; Nervous system (semeiology, syndromes) ; Neurology ; Registries ; Switzerland - epidemiology</subject><ispartof>Acta pædiatrica (Oslo), 2005-05, Vol.94 (5), p.564-567</ispartof><rights>2005 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c329t-8aa6e11707a477b6662b13047c4d60c7f9e40586aaded0df35463a3d31465f593</citedby><cites>FETCH-LOGICAL-c329t-8aa6e11707a477b6662b13047c4d60c7f9e40586aaded0df35463a3d31465f593</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=16733372$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16188745$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>WEBER, Peter</creatorcontrib><creatorcontrib>BUBL, Reinhard</creatorcontrib><creatorcontrib>BLAUENSTEIN, Ursula</creatorcontrib><creatorcontrib>TILLMANN, Bettina U</creatorcontrib><creatorcontrib>LÜTSCHG, Jürg</creatorcontrib><title>Sudden unexplained death in children with epilepsy : A cohort study with an eighteen-year follow-up</title><title>Acta pædiatrica (Oslo)</title><addtitle>Acta Paediatr</addtitle><description>Sudden unexplained death is a significant cause of mortality in adults with epilepsy. Only a few data exist about this risk in childhood.
Cases of sudden unexplained death in epilepsy (SUDEP) up to the age of 18 y occurring at our hospital between 1984 and 2001 were identified. The incidence rate was calculated on the basis of diagnosed epileptics registered with a statutory disability insurance scheme.
Four cases of SUDEP were identified during the 18-y period. The incidence of SUDEP was 4.3 per 10,000 patient-years. All children showed polytherapy-refractory epilepsy, developmental retardation and early-onset epilepsy. Two witnessed cases had shown no previous signs of seizure.
SUDEP is rare in childhood. Children with uncomplicated epilepsy seem not to be at risk.</description><subject>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy</subject><subject>Anticonvulsants - therapeutic use</subject><subject>Biological and medical sciences</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Cohort Studies</subject><subject>Death, Sudden - epidemiology</subject><subject>Developmental Disabilities - complications</subject><subject>Emergency and intensive care: neonates and children. Prematurity. Sudden death</subject><subject>Epilepsy - complications</subject><subject>Epilepsy - drug therapy</subject><subject>Epilepsy - epidemiology</subject><subject>Female</subject><subject>General aspects</subject><subject>Headache. Facial pains. Syncopes. Epilepsia. Intracranial hypertension. Brain oedema. Cerebral palsy</subject><subject>Humans</subject><subject>Incidence</subject><subject>Infant</subject><subject>Intensive care medicine</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Nervous system (semeiology, syndromes)</subject><subject>Neurology</subject><subject>Registries</subject><subject>Switzerland - epidemiology</subject><issn>0803-5253</issn><issn>1651-2227</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2005</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNplkEtLw0AUhQdRbK3-ADcyG91F5z2pOym-oOBCXYfpzI0ZmSZxJqHm35vSgoKLy4F7vnMWB6FzSq4pycnNeFwySQQlhPFcswM0pUrSjDGmD9F062cjwCfoJKVPQojgWhyjCVU0z7WQU2Rfe-egxn0N320wvgaHHZiuwr7GtvLBxdHd-PEBrQ_QpgHf4jtsm6qJHU5d74adbWoM_qPqAOpsABNx2YTQbLK-PUVHpQkJzvY6Q-8P92-Lp2z58vi8uFtmlrN5l-XGKKBUE22E1iulFFtRToS2wilidTkHQWSujHHgiCu5FIob7jgVSpZyzmfoatfbxuarh9QVa58shGBqaPpUqFxxJnI9gnQH2tikFKEs2ujXJg4FJcV22eLfsmPmYl_er9bgfhP7KUfgcg-YZE0oo6mtT384zTkfi34AFs9_uw</recordid><startdate>20050501</startdate><enddate>20050501</enddate><creator>WEBER, Peter</creator><creator>BUBL, Reinhard</creator><creator>BLAUENSTEIN, Ursula</creator><creator>TILLMANN, Bettina U</creator><creator>LÜTSCHG, Jürg</creator><general>Blackwell</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20050501</creationdate><title>Sudden unexplained death in children with epilepsy : A cohort study with an eighteen-year follow-up</title><author>WEBER, Peter ; BUBL, Reinhard ; BLAUENSTEIN, Ursula ; TILLMANN, Bettina U ; LÜTSCHG, Jürg</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c329t-8aa6e11707a477b6662b13047c4d60c7f9e40586aaded0df35463a3d31465f593</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2005</creationdate><topic>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy</topic><topic>Anticonvulsants - therapeutic use</topic><topic>Biological and medical sciences</topic><topic>Child</topic><topic>Child, Preschool</topic><topic>Cohort Studies</topic><topic>Death, Sudden - epidemiology</topic><topic>Developmental Disabilities - complications</topic><topic>Emergency and intensive care: neonates and children. Prematurity. Sudden death</topic><topic>Epilepsy - complications</topic><topic>Epilepsy - drug therapy</topic><topic>Epilepsy - epidemiology</topic><topic>Female</topic><topic>General aspects</topic><topic>Headache. Facial pains. Syncopes. Epilepsia. Intracranial hypertension. Brain oedema. Cerebral palsy</topic><topic>Humans</topic><topic>Incidence</topic><topic>Infant</topic><topic>Intensive care medicine</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Nervous system (semeiology, syndromes)</topic><topic>Neurology</topic><topic>Registries</topic><topic>Switzerland - epidemiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>WEBER, Peter</creatorcontrib><creatorcontrib>BUBL, Reinhard</creatorcontrib><creatorcontrib>BLAUENSTEIN, Ursula</creatorcontrib><creatorcontrib>TILLMANN, Bettina U</creatorcontrib><creatorcontrib>LÜTSCHG, Jürg</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Acta pædiatrica (Oslo)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>WEBER, Peter</au><au>BUBL, Reinhard</au><au>BLAUENSTEIN, Ursula</au><au>TILLMANN, Bettina U</au><au>LÜTSCHG, Jürg</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Sudden unexplained death in children with epilepsy : A cohort study with an eighteen-year follow-up</atitle><jtitle>Acta pædiatrica (Oslo)</jtitle><addtitle>Acta Paediatr</addtitle><date>2005-05-01</date><risdate>2005</risdate><volume>94</volume><issue>5</issue><spage>564</spage><epage>567</epage><pages>564-567</pages><issn>0803-5253</issn><eissn>1651-2227</eissn><abstract>Sudden unexplained death is a significant cause of mortality in adults with epilepsy. Only a few data exist about this risk in childhood.
Cases of sudden unexplained death in epilepsy (SUDEP) up to the age of 18 y occurring at our hospital between 1984 and 2001 were identified. The incidence rate was calculated on the basis of diagnosed epileptics registered with a statutory disability insurance scheme.
Four cases of SUDEP were identified during the 18-y period. The incidence of SUDEP was 4.3 per 10,000 patient-years. All children showed polytherapy-refractory epilepsy, developmental retardation and early-onset epilepsy. Two witnessed cases had shown no previous signs of seizure.
SUDEP is rare in childhood. Children with uncomplicated epilepsy seem not to be at risk.</abstract><cop>Oxford</cop><pub>Blackwell</pub><pmid>16188745</pmid><doi>10.1080/08035250410023872</doi><tpages>4</tpages></addata></record> |
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| source | MEDLINE; Wiley Online Library Journals Frontfile Complete |
| subjects | Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Anticonvulsants - therapeutic use Biological and medical sciences Child Child, Preschool Cohort Studies Death, Sudden - epidemiology Developmental Disabilities - complications Emergency and intensive care: neonates and children. Prematurity. Sudden death Epilepsy - complications Epilepsy - drug therapy Epilepsy - epidemiology Female General aspects Headache. Facial pains. Syncopes. Epilepsia. Intracranial hypertension. Brain oedema. Cerebral palsy Humans Incidence Infant Intensive care medicine Male Medical sciences Nervous system (semeiology, syndromes) Neurology Registries Switzerland - epidemiology |
| title | Sudden unexplained death in children with epilepsy : A cohort study with an eighteen-year follow-up |
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