LOH at 6p21.3 region and HLA class I altered phenotypes in bladder carcinomas

Alterations in HLA class I antigen expression have been frequently described in different epithelial tumors and are thought to favor tumor immune escape from T lymphocyte recognition. Multiple molecular mechanisms are responsible for these altered HLA class I tumor phenotypes. Some are structural de...

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Veröffentlicht in:	Immunogenetics (New York) 2006-07, Vol.58 (7), p.503-510
Hauptverfasser:	Maleno, Isabel, Romero, Jose Maria, Cabrera, Teresa, Paco, Laura, Aptsiauri, Natalia, Cozar, Jose Manuel, Tallada, Miguel, López-Nevot, Miguel Angel, Garrido, Federico
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Carcinoma, Transitional Cell - genetics Carcinoma, Transitional Cell - immunology Chromosomes, Human, Pair 6 - genetics Gene Expression HLA Antigens - genetics Humans Loss of Heterozygosity Microsatellite Repeats Molecular Sequence Data Phenotype Urinary Bladder Neoplasms - genetics Urinary Bladder Neoplasms - immunology
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