First case series on the use of imiquimod for morphoea

Summary Background Morphoea is characterized by fibrosis, which is mediated by cytokines including transforming growth factor (TGF)‐β. Objective Our objective was to use imiquimod 5% cream (Aldara™), an inducer of interferon‐γ, known to inhibit TGF‐β, to treat morphoea. Methods Patients with morp...

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Veröffentlicht in:	British journal of dermatology (1951) 2005-10, Vol.153 (4), p.815-820
Hauptverfasser:	Dytoc, M., Ting, P.T., Man, J., Sawyer, D., Fiorillo, L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Cutaneous Adolescent Adult Aged Aminoquinolines - therapeutic use Biological and medical sciences Child cytokines Drug Evaluation Female Follow-Up Studies Humans imiquimod Interferon Inducers - therapeutic use localized scleroderma Male Medical sciences Middle Aged morphoea Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis Scleroderma, Localized - drug therapy Scleroderma, Localized - pathology Severity of Illness Index Treatment Outcome
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