Multiple Treatment Approach to Limit Cardiac Ischemia-Reperfusion Injury

This study evaluates a multiple treatment approach (ie, pharmacologic preconditioning [diazoxide], sodium-proton exchange inhibition [cariporide], and controlled reperfusion) to improve the outcome from severe cardiac ischemia-reperfusion injury that occurs during a cardiac operation. Five groups of...

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Veröffentlicht in:	The Annals of thoracic surgery 2005-10, Vol.80 (4), p.1408-1416
Hauptverfasser:	Davies, James E., Digerness, Stanley B., Killingsworth, Cheryl R., Zaragoza, Corinne, Katholi, Charles R., Justice, Robert K., Goldberg, Steven P., Holman, William L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anti-Arrhythmia Agents - therapeutic use Cardiac Surgical Procedures - adverse effects Combined Modality Therapy - methods Diazoxide - therapeutic use Disease Models, Animal Drug Therapy, Combination Female Guanidines - therapeutic use Male Myocardial Infarction - complications Myocardial Infarction - pathology Myocardial Infarction - therapy Myocardial Reperfusion Injury - etiology Myocardial Reperfusion Injury - pathology Myocardial Reperfusion Injury - physiopathology Myocardial Reperfusion Injury - prevention & control Recovery of Function Reference Values Sulfones - therapeutic use Swine Treatment Outcome Vasodilator Agents - therapeutic use Ventricular Dysfunction, Left - etiology Ventricular Dysfunction, Left - physiopathology
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