Efficient selection of tagging single-nucleotide polymorphisms in multiple populations

Common genetic polymorphism may explain a portion of the heritable risk for common diseases, so considerable effort has been devoted to finding and typing common single-nucleotide polymorphisms (SNPs) in the human genome. Many SNPs show correlated genotypes, or linkage disequilibrium (LD), suggestin...

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Veröffentlicht in:	Human genetics 2006-08, Vol.120 (1), p.58-68
Hauptverfasser:	HOWIE, Bryan N, CARLSON, Christopher S, RIEDER, Mark J, NICKERSON, Deborah A
Format:	Artikel
Sprache:	eng
Schlagworte:	African Continental Ancestry Group - genetics Algorithms Asian Continental Ancestry Group - genetics Biological and medical sciences Chromosomes Classical genetics, quantitative genetics, hybrids European Continental Ancestry Group - genetics Fundamental and applied biological sciences. Psychology Genetics of eukaryotes. Biological and molecular evolution Genetics, Population Genomes Genotype Human Humans Linkage Disequilibrium Polymorphism, Single Nucleotide - genetics
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