Autofluorescence removal, multiplexing, and automated analysis methods for in-vivo fluorescence imaging

The ability to image and quantitate fluorescently labeled markers in vivo has generally been limited by autofluorescence of the tissue. Skin, in particular, has a strong autofluorescence signal, particularly when excited in the blue or green wavelengths. Fluorescence labels with emission wavelengths...

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Veröffentlicht in:	Journal of biomedical optics 2005-07, Vol.10 (4), p.41207-1/041207-9
Hauptverfasser:	Mansfield, James R, Gossage, Kirk W, Hoyt, Clifford C, Levenson, Richard M
Format:	Artikel
Sprache:	eng
Schlagworte:	Algorithms Animals Image Enhancement - methods Image Interpretation, Computer-Assisted - methods Luminescent Proteins - metabolism Male Mice Microscopy, Fluorescence - instrumentation Microscopy, Fluorescence - methods Neoplasm Proteins - metabolism Phantoms, Imaging Prostatic Neoplasms - metabolism Prostatic Neoplasms - pathology Quantum Dots Reproducibility of Results Sensitivity and Specificity
Online-Zugang:	Volltext
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