C-Type Natriuretic Peptide Relaxes Human Coronary Artery Bypass Grafts Preconstricted by Endothelin-1

Endothelin is implicated in graft spasm after coronary artery bypass grafting. We assessed reversal by the endothelium-derived vasodilator C-type natriuretic peptide of prior contraction of radial artery and other vessels commonly used for coronary artery bypass surgery. Segments of human radial art...

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Veröffentlicht in:	The Annals of thoracic surgery 2005-10, Vol.80 (4), p.1347-1351
Hauptverfasser:	Kelsall, Christopher J., Chester, Adrian H., Amrani, Mohammed, Singer, Donald R.J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylcholine - pharmacology Biological and medical sciences Cardiology. Vascular system Coronary Artery Bypass Coronary heart disease Coronary Vasospasm - prevention & control Dose-Response Relationship, Drug Endothelin-1 - antagonists & inhibitors Heart Humans In Vitro Techniques Mammary Arteries - drug effects Medical sciences Middle Aged Natriuretic Agents - pharmacology Natriuretic Peptide, C-Type - pharmacology Papaverine - pharmacology Radial Artery - drug effects Saphenous Vein - drug effects Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Surgery of the respiratory system Transplants Treatment Outcome Vasoconstriction - drug effects Vasodilator Agents - pharmacology
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