The prognostic impact of histology and 1p/19q status in anaplastic oligodendroglial tumors

BACKGROUND It has been reported previously that the combined loss of chromosomal arms 1p and 19q is a significant predictor of outcome for patients with anaplastic oligodendroglial (AO) tumors and that such chromosomal loss correlates with classic histology in AO. The authors sought to determine whe...

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Veröffentlicht in:	Cancer 2005-10, Vol.104 (7), p.1468-1477
Hauptverfasser:	McDonald, J. Matthew, See, Siew Ju, Tremont, Ivo W., Colman, Howard, Gilbert, Mark R., Groves, Morris, Burger, Peter C., Louis, David N., Giannini, Caterina, Fuller, Gregory, Passe, Sandra, Blair, Hilary, Jenkins, Robert B., Yang, Helen, Ledoux, Alicia, Aaron, Joann, Tipnis, Ulka, Zhang, Wei, Hess, Kenneth, Aldape, Ken
Format:	Artikel
Sprache:	eng
Schlagworte:	1p/19q status Base Sequence Biological and medical sciences Biopsy, Needle Brain Neoplasms - genetics Brain Neoplasms - mortality Brain Neoplasms - pathology Brain Neoplasms - surgery Chromosomes, Human, Pair 1 Chromosomes, Human, Pair 19 Cohort Studies DNA, Neoplasm - analysis Female Genetic Markers - genetics Humans In Situ Hybridization, Fluorescence Logistic Models Loss of Heterozygosity Male Medical sciences Molecular Sequence Data monomorphic pattern Neoplasm Staging Neurology nonrandom allelic loss oligodendroglioma Oligodendroglioma - genetics Oligodendroglioma - mortality Oligodendroglioma - pathology Oligodendroglioma - surgery Polymerase Chain Reaction - methods Prognosis Retrospective Studies Risk Assessment survival Survival Analysis Tumors Tumors of the nervous system. Phacomatoses
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