Nanotechnology : Intelligent design to treat complex disease
The purpose of this expert review is to discuss the impact of nanotechnology in the treatment of the major health threats including cancer, infections, metabolic diseases, autoimmune diseases, and inflammations. Indeed, during the past 30 years, the explosive growth of nanotechnology has burst into...
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| Veröffentlicht in: | Pharmaceutical research 2006-07, Vol.23 (7), p.1417-1450 |
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| creator | COUVREUR, Patrick VAUTHIER, Christine |
| description | The purpose of this expert review is to discuss the impact of nanotechnology in the treatment of the major health threats including cancer, infections, metabolic diseases, autoimmune diseases, and inflammations. Indeed, during the past 30 years, the explosive growth of nanotechnology has burst into challenging innovations in pharmacology, the main input being the ability to perform temporal and spatial site-specific delivery. This has led to some marketed compounds through the last decade. Although the introduction of nanotechnology obviously permitted to step over numerous milestones toward the development of the "magic bullet" proposed a century ago by the immunologist Paul Ehrlich, there are, however, unresolved delivery problems to be still addressed. These scientific and technological locks are discussed along this review together with an analysis of the current situation concerning the industrial development. |
| doi_str_mv | 10.1007/s11095-006-0284-8 |
| format | Article |
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Indeed, during the past 30 years, the explosive growth of nanotechnology has burst into challenging innovations in pharmacology, the main input being the ability to perform temporal and spatial site-specific delivery. This has led to some marketed compounds through the last decade. Although the introduction of nanotechnology obviously permitted to step over numerous milestones toward the development of the "magic bullet" proposed a century ago by the immunologist Paul Ehrlich, there are, however, unresolved delivery problems to be still addressed. 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Pharmaceutical industry</subject><subject>Pharmacology</subject><subject>Pharmacology. 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Pharmaceutical industry</topic><topic>Pharmacology</topic><topic>Pharmacology. 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| subjects | Animals Anti-Infective Agents - administration & dosage Antineoplastic Agents - administration & dosage Autoimmune diseases Biodistribution Biological and medical sciences Cancer therapies Drug delivery systems Drug Delivery Systems - economics Drug Delivery Systems - trends Drug Industry - economics Drug Industry - trends General pharmacology Humans Hypoglycemic Agents - administration & dosage Infectious diseases Intelligent design Medical innovations Medical sciences Metabolic disorders Nanoparticles Nanotechnology Nanotechnology - economics Nanotechnology - trends Nosocomial infections Pharmaceutical technology. Pharmaceutical industry Pharmacology Pharmacology. Drug treatments Technology, Pharmaceutical - economics Technology, Pharmaceutical - trends Toxicity Tropical diseases |
| title | Nanotechnology : Intelligent design to treat complex disease |
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