Notch pathway repression by vestigial is required to promote indirect flight muscle differentiation in Drosophila melanogaster

Drosophila dorsal longitudinal muscles develop during metamorphosis by fusion of myoblasts with larval templates. It has been shown that both vestigial and Notch are crucial for correct formation of these muscles. We investigated the relationship between vestigial and the Notch pathway during this p...

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Veröffentlicht in:	Developmental biology 2006-07, Vol.295 (1), p.164-177
Hauptverfasser:	Bernard, F., Dutriaux, A., Silber, J., Lalouette, A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Calcium-Binding Proteins - genetics Calcium-Binding Proteins - metabolism Cell Differentiation - genetics Dorsal longitudinal muscles Drosophila melanogaster Drosophila melanogaster - growth & development Drosophila Proteins - genetics Drosophila Proteins - metabolism Gene Expression Regulation, Developmental Intercellular Signaling Peptides and Proteins Jagged-1 Protein Membrane Proteins - genetics Membrane Proteins - metabolism Muscle Fibers, Skeletal - cytology Muscle Fibers, Skeletal - physiology Muscles - cytology Muscles - physiology Mutation Myoblasts - cytology Myoblasts - physiology Myogenesis N-Acetylglucosaminyltransferases - genetics N-Acetylglucosaminyltransferases - metabolism Notch pathway Nuclear Proteins - genetics Nuclear Proteins - metabolism Phosphoproteins - genetics Phosphoproteins - metabolism Receptors, Notch - genetics Receptors, Notch - metabolism Serrate-Jagged Proteins Signal Transduction Transcription Factors - genetics Transcription Factors - metabolism Ubiquitin-Protein Ligases - genetics Ubiquitin-Protein Ligases - metabolism Vestigial Wings, Animal - growth & development
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