Collie eye anomaly in a mixed-breed dog
A 5-year-old, mixed-breed dog was presented for tetraparesis. Neurologic alterations included a decreased menace response in both eyes. Therefore, an ophthalmic examination was requested. The dog was visual, but menace response, dazzle and pupillary light reflexes were reduced bilaterally. Indirect...
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Veröffentlicht in: | Veterinary ophthalmology 2005-09, Vol.8 (5), p.357-360 |
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description | A 5-year-old, mixed-breed dog was presented for tetraparesis. Neurologic alterations included a decreased menace response in both eyes. Therefore, an ophthalmic examination was requested. The dog was visual, but menace response, dazzle and pupillary light reflexes were reduced bilaterally. Indirect ophthalmoscopy revealed bilateral optic nerve coloboma and severe choroidal hypoplasia. These lesions closely resembled the ophthalmoscopic features of Collie eye anomaly (CEA). In spite of treatment, the dog's condition worsened and the animal was therefore euthanized. Histology of the globes confirmed severe choroidal hypoplasia and optic disc coloboma in both eyes. The dog was diagnosed to have a lymphoma involving the spinal cord. The two entities were considered not related. As only moderate sight impairment was caused by the posterior segment anomalies, it is by chance that these lesions resembling CEA were found in this mixed-breed dog. |
doi_str_mv | 10.1111/j.1463-5224.2005.00417.x |
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Neurologic alterations included a decreased menace response in both eyes. Therefore, an ophthalmic examination was requested. The dog was visual, but menace response, dazzle and pupillary light reflexes were reduced bilaterally. Indirect ophthalmoscopy revealed bilateral optic nerve coloboma and severe choroidal hypoplasia. These lesions closely resembled the ophthalmoscopic features of Collie eye anomaly (CEA). In spite of treatment, the dog's condition worsened and the animal was therefore euthanized. Histology of the globes confirmed severe choroidal hypoplasia and optic disc coloboma in both eyes. The dog was diagnosed to have a lymphoma involving the spinal cord. The two entities were considered not related. As only moderate sight impairment was caused by the posterior segment anomalies, it is by chance that these lesions resembling CEA were found in this mixed-breed dog.</description><identifier>ISSN: 1463-5216</identifier><identifier>EISSN: 1463-5224</identifier><identifier>DOI: 10.1111/j.1463-5224.2005.00417.x</identifier><identifier>PMID: 16178848</identifier><language>eng</language><publisher>Oxford, UK: Blackwell Science Ltd</publisher><subject>Animals ; case studies ; Choroid - abnormalities ; choroidal hypoplasia ; Collie eye anomaly ; coloboma ; Coloboma - diagnosis ; Coloboma - pathology ; Coloboma - veterinary ; congenital abnormalities ; crossbreds ; dog diseases ; Dog Diseases - diagnosis ; Dog Diseases - pathology ; Dogs ; Eye Abnormalities - diagnosis ; Eye Abnormalities - pathology ; Eye Abnormalities - veterinary ; eye diseases ; Fatal Outcome ; Fundus Oculi ; German Shepherd ; Golden Retriever ; hypoplasia ; lesions (animal) ; lymphoma ; Lymphoma - complications ; Lymphoma - veterinary ; mixed‐breed dog ; optic disc coloboma ; Optic Nerve - abnormalities ; peripheral nerves ; Quadriplegia - etiology ; Quadriplegia - veterinary ; spinal cord ; Spinal Cord Neoplasms - complications ; Spinal Cord Neoplasms - veterinary ; vision</subject><ispartof>Veterinary ophthalmology, 2005-09, Vol.8 (5), p.357-360</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4587-a638c5c52f104745bb1fb52f1d738029693e76842c00f27f8dbda6fd32936e9f3</citedby><cites>FETCH-LOGICAL-c4587-a638c5c52f104745bb1fb52f1d738029693e76842c00f27f8dbda6fd32936e9f3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fj.1463-5224.2005.00417.x$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fj.1463-5224.2005.00417.x$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,27903,27904,45553,45554</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16178848$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Rampazzo, A</creatorcontrib><creatorcontrib>D'Angelo, A</creatorcontrib><creatorcontrib>Capucchio, M.T</creatorcontrib><creatorcontrib>Sereno, S</creatorcontrib><creatorcontrib>Peruccio, C</creatorcontrib><title>Collie eye anomaly in a mixed-breed dog</title><title>Veterinary ophthalmology</title><addtitle>Vet Ophthalmol</addtitle><description>A 5-year-old, mixed-breed dog was presented for tetraparesis. Neurologic alterations included a decreased menace response in both eyes. Therefore, an ophthalmic examination was requested. The dog was visual, but menace response, dazzle and pupillary light reflexes were reduced bilaterally. Indirect ophthalmoscopy revealed bilateral optic nerve coloboma and severe choroidal hypoplasia. These lesions closely resembled the ophthalmoscopic features of Collie eye anomaly (CEA). In spite of treatment, the dog's condition worsened and the animal was therefore euthanized. Histology of the globes confirmed severe choroidal hypoplasia and optic disc coloboma in both eyes. The dog was diagnosed to have a lymphoma involving the spinal cord. The two entities were considered not related. As only moderate sight impairment was caused by the posterior segment anomalies, it is by chance that these lesions resembling CEA were found in this mixed-breed dog.</description><subject>Animals</subject><subject>case studies</subject><subject>Choroid - abnormalities</subject><subject>choroidal hypoplasia</subject><subject>Collie eye anomaly</subject><subject>coloboma</subject><subject>Coloboma - diagnosis</subject><subject>Coloboma - pathology</subject><subject>Coloboma - veterinary</subject><subject>congenital abnormalities</subject><subject>crossbreds</subject><subject>dog diseases</subject><subject>Dog Diseases - diagnosis</subject><subject>Dog Diseases - pathology</subject><subject>Dogs</subject><subject>Eye Abnormalities - diagnosis</subject><subject>Eye Abnormalities - pathology</subject><subject>Eye Abnormalities - veterinary</subject><subject>eye diseases</subject><subject>Fatal Outcome</subject><subject>Fundus Oculi</subject><subject>German Shepherd</subject><subject>Golden Retriever</subject><subject>hypoplasia</subject><subject>lesions (animal)</subject><subject>lymphoma</subject><subject>Lymphoma - complications</subject><subject>Lymphoma - veterinary</subject><subject>mixed‐breed dog</subject><subject>optic disc coloboma</subject><subject>Optic Nerve - abnormalities</subject><subject>peripheral nerves</subject><subject>Quadriplegia - etiology</subject><subject>Quadriplegia - veterinary</subject><subject>spinal cord</subject><subject>Spinal Cord Neoplasms - complications</subject><subject>Spinal Cord Neoplasms - veterinary</subject><subject>vision</subject><issn>1463-5216</issn><issn>1463-5224</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2005</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkE1Lw0AQhhdRrFb_guakp8TZ781FkOIXFCpovS6b7G5JSZqatdj8e5Om1KtzmRnmnXeYB6EIQ4K7uFsmmAkac0JYQgB4AsCwTLZH6OwwOD7UWIzQeQhLAKAc5CkaYYGlUkydodtJXZaFi1zrIrOqK1O2UbGKTFQVW2fjrHHORrZeXKATb8rgLvd5jOZPjx-Tl3g6e36dPEzjnHElYyOoynnOicfAJONZhn3Wd1ZSBSQVKXVSKEZyAE-kVzazRnhLSUqFSz0do5vBd93UXxsXvnVVhNyVpVm5ehO0UAJDSnknVIMwb-oQGuf1uikq07Qag-4h6aXu_9c9C91D0jtIetutXu1vbLLK2b_FPZVOcD8IforStf821p-zt13ZGVwPBt7U2iyaIuj5OwFMAQOVlCv6C0jvfAE</recordid><startdate>200509</startdate><enddate>200509</enddate><creator>Rampazzo, A</creator><creator>D'Angelo, A</creator><creator>Capucchio, M.T</creator><creator>Sereno, S</creator><creator>Peruccio, C</creator><general>Blackwell Science Ltd</general><scope>FBQ</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>200509</creationdate><title>Collie eye anomaly in a mixed-breed dog</title><author>Rampazzo, A ; D'Angelo, A ; Capucchio, M.T ; Sereno, S ; Peruccio, C</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4587-a638c5c52f104745bb1fb52f1d738029693e76842c00f27f8dbda6fd32936e9f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2005</creationdate><topic>Animals</topic><topic>case studies</topic><topic>Choroid - abnormalities</topic><topic>choroidal hypoplasia</topic><topic>Collie eye anomaly</topic><topic>coloboma</topic><topic>Coloboma - diagnosis</topic><topic>Coloboma - pathology</topic><topic>Coloboma - veterinary</topic><topic>congenital abnormalities</topic><topic>crossbreds</topic><topic>dog diseases</topic><topic>Dog Diseases - diagnosis</topic><topic>Dog Diseases - pathology</topic><topic>Dogs</topic><topic>Eye Abnormalities - diagnosis</topic><topic>Eye Abnormalities - pathology</topic><topic>Eye Abnormalities - veterinary</topic><topic>eye diseases</topic><topic>Fatal Outcome</topic><topic>Fundus Oculi</topic><topic>German Shepherd</topic><topic>Golden Retriever</topic><topic>hypoplasia</topic><topic>lesions (animal)</topic><topic>lymphoma</topic><topic>Lymphoma - complications</topic><topic>Lymphoma - veterinary</topic><topic>mixed‐breed dog</topic><topic>optic disc coloboma</topic><topic>Optic Nerve - abnormalities</topic><topic>peripheral nerves</topic><topic>Quadriplegia - etiology</topic><topic>Quadriplegia - veterinary</topic><topic>spinal cord</topic><topic>Spinal Cord Neoplasms - complications</topic><topic>Spinal Cord Neoplasms - veterinary</topic><topic>vision</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Rampazzo, A</creatorcontrib><creatorcontrib>D'Angelo, A</creatorcontrib><creatorcontrib>Capucchio, M.T</creatorcontrib><creatorcontrib>Sereno, S</creatorcontrib><creatorcontrib>Peruccio, C</creatorcontrib><collection>AGRIS</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Veterinary ophthalmology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Rampazzo, A</au><au>D'Angelo, A</au><au>Capucchio, M.T</au><au>Sereno, S</au><au>Peruccio, C</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Collie eye anomaly in a mixed-breed dog</atitle><jtitle>Veterinary ophthalmology</jtitle><addtitle>Vet Ophthalmol</addtitle><date>2005-09</date><risdate>2005</risdate><volume>8</volume><issue>5</issue><spage>357</spage><epage>360</epage><pages>357-360</pages><issn>1463-5216</issn><eissn>1463-5224</eissn><abstract>A 5-year-old, mixed-breed dog was presented for tetraparesis. Neurologic alterations included a decreased menace response in both eyes. Therefore, an ophthalmic examination was requested. The dog was visual, but menace response, dazzle and pupillary light reflexes were reduced bilaterally. Indirect ophthalmoscopy revealed bilateral optic nerve coloboma and severe choroidal hypoplasia. These lesions closely resembled the ophthalmoscopic features of Collie eye anomaly (CEA). In spite of treatment, the dog's condition worsened and the animal was therefore euthanized. Histology of the globes confirmed severe choroidal hypoplasia and optic disc coloboma in both eyes. The dog was diagnosed to have a lymphoma involving the spinal cord. The two entities were considered not related. As only moderate sight impairment was caused by the posterior segment anomalies, it is by chance that these lesions resembling CEA were found in this mixed-breed dog.</abstract><cop>Oxford, UK</cop><pub>Blackwell Science Ltd</pub><pmid>16178848</pmid><doi>10.1111/j.1463-5224.2005.00417.x</doi><tpages>4</tpages></addata></record> |
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subjects | Animals case studies Choroid - abnormalities choroidal hypoplasia Collie eye anomaly coloboma Coloboma - diagnosis Coloboma - pathology Coloboma - veterinary congenital abnormalities crossbreds dog diseases Dog Diseases - diagnosis Dog Diseases - pathology Dogs Eye Abnormalities - diagnosis Eye Abnormalities - pathology Eye Abnormalities - veterinary eye diseases Fatal Outcome Fundus Oculi German Shepherd Golden Retriever hypoplasia lesions (animal) lymphoma Lymphoma - complications Lymphoma - veterinary mixed‐breed dog optic disc coloboma Optic Nerve - abnormalities peripheral nerves Quadriplegia - etiology Quadriplegia - veterinary spinal cord Spinal Cord Neoplasms - complications Spinal Cord Neoplasms - veterinary vision |
title | Collie eye anomaly in a mixed-breed dog |
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