Analysis of minK and eNOS genes as candidate loci for predisposition to non-valvular atrial fibrillation

Mink protein, a beta-subunit of I(ks) potassium channels modulate cardiac cellular electrophysiology, and experimental data demonstrated that NO is involved in cardiac vagal activity and in the inhibition of sympathetic activity. We evaluated the role of eNOS -786T>C, 894G>T, 4a/4b and of minK...

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Veröffentlicht in:	European heart journal 2006-07, Vol.27 (14), p.1712-1718
Hauptverfasser:	Fatini, Cinzia, Sticchi, Elena, Genuardi, Maurizio, Sofi, Francesco, Gensini, Francesca, Gori, Anna Maria, Lenti, Meri, Michelucci, Antonio, Abbate, Rosanna, Gensini, Gian Franco
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Atrial Fibrillation - genetics Case-Control Studies Female Gene Frequency Genetic Predisposition to Disease - genetics Genotype Humans Male Nitric Oxide Synthase Type III - genetics Polymerase Chain Reaction - methods Polymorphism, Genetic - genetics Polymorphism, Restriction Fragment Length Potassium Channels, Voltage-Gated - genetics
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