Membrane trafficking at the ER/Golgi interface: Functional implications of RhoA and Rac1

N-WASP and Arp2/3, the components of the actin nucleation/polymerization signaling pathway governed by Cdc42, are located in Golgi membranes and regulate ER/Golgi interface protein transport. In the present study, we examined whether RhoA and Rac1, like Cdc42, are also involved in this early secreto...

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Veröffentlicht in:	European journal of cell biology 2005-08, Vol.84 (8), p.699-707
Hauptverfasser:	Matas, Olga B., Fritz, Stefan, Luna, Ana, Egea, Gustavo
Format:	Artikel
Sprache:	eng
Schlagworte:	Actin Animals Biological Transport - physiology cdc42 GTP-Binding Protein - genetics cdc42 GTP-Binding Protein - metabolism Cell Line Cytoskeleton Endoplasmic Reticulum - metabolism Endoplasmic Reticulum - ultrastructure ER/Golgi interface Golgi apparatus Golgi Apparatus - metabolism Golgi Apparatus - ultrastructure Humans Intracellular Membranes - metabolism Microinjections rac1 GTP-Binding Protein - genetics rac1 GTP-Binding Protein - metabolism Rats Receptors, Peptide - metabolism Recombinant Fusion Proteins - genetics Recombinant Fusion Proteins - metabolism Rho GTPases rhoA GTP-Binding Protein - genetics rhoA GTP-Binding Protein - metabolism Secretory pathway Transfection Vesicular stomatitis Indiana virus - metabolism
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