Invasive group A streptococcal infection with pancarditis caused by a new emm-type 12 allele of Streptococcus pyogenes
Throughout the 1980s, a progressive increase in the incidence of Streptococcus pyogenes-related invasive infections has occurred. It has been suggested that a host-related immunogenetic background, as well as bacterial virulence factors may play an important role in the outcome of streptococcal infe...
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Veröffentlicht in: | The Journal of infection 2006-07, Vol.53 (1), p.e1-e4 |
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container_title | The Journal of infection |
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creator | Özkaya, Gülşen Shorbagi, Ali Ülger, Zekeriya Saglam, Arzu Aybar, Melda Şardan, Yeşim Çetinkaya Uzun, Ömrüm |
description | Throughout the 1980s, a progressive increase in the incidence of
Streptococcus pyogenes-related invasive infections has occurred. It has been suggested that a host-related immunogenetic background, as well as bacterial virulence factors may play an important role in the outcome of streptococcal infections. Here, we present the first case of pancarditis in the literature caused by direct bacterial invasion due to a new
emm-type 12 allele of
S. pyogenes in an immunocompetent patient. The pathogenesis of this invasive infection, as well as predictors of poor prognosis are discussed. |
doi_str_mv | 10.1016/j.jinf.2005.10.006 |
format | Article |
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Streptococcus pyogenes-related invasive infections has occurred. It has been suggested that a host-related immunogenetic background, as well as bacterial virulence factors may play an important role in the outcome of streptococcal infections. Here, we present the first case of pancarditis in the literature caused by direct bacterial invasion due to a new
emm-type 12 allele of
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Streptococcus pyogenes-related invasive infections has occurred. It has been suggested that a host-related immunogenetic background, as well as bacterial virulence factors may play an important role in the outcome of streptococcal infections. Here, we present the first case of pancarditis in the literature caused by direct bacterial invasion due to a new
emm-type 12 allele of
S. pyogenes in an immunocompetent patient. The pathogenesis of this invasive infection, as well as predictors of poor prognosis are discussed.</description><subject>Adult</subject><subject>Alleles</subject><subject>Antigens, Bacterial - genetics</subject><subject>Bacterial Outer Membrane Proteins - genetics</subject><subject>Carrier Proteins - genetics</subject><subject>emm-Type 12 allele</subject><subject>Fatal Outcome</subject><subject>Female</subject><subject>Humans</subject><subject>Invasive infection</subject><subject>Myocarditis - microbiology</subject><subject>Pancarditis</subject><subject>Sepsis - microbiology</subject><subject>Streptococcal Infections - microbiology</subject><subject>Streptococcus pyogenes</subject><subject>Streptococcus pyogenes - classification</subject><subject>Streptococcus pyogenes - genetics</subject><subject>Streptococcus pyogenes - isolation & purification</subject><issn>0163-4453</issn><issn>1532-2742</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2006</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkU9LwzAYh4Mobk6_gAfJyVtnmqTpCl5E_AcDD-o5pMnbmdE2NWk39u1N2WA3zSXw43l_L7wPQtcpmackFXfr-dq21ZwSksVgTog4QdM0YzShOaenaBohlnCesQm6CGFNCClYIc7RJOaCxzdFm7d2o4LdAF55N3T4AYfeQ9c77bRWNY4LQPfWtXhr-2_cqVYrb2xvA9ZqCGBwucMKt7DF0DRJv-sApxSruoYasKvwx7FuCLjbuRW0EC7RWaXqAFeHf4a-np8-H1-T5fvL2-PDMtGMkD4RQi8KKEtqqKp4JgzkUGlORWEKxWOkSs0YzytOFQi2KAquDckMLwwDWnI2Q7f73s67nwFCLxsbNNS1asENQYqFICJP83_BNKdxvxhBuge1dyF4qGTnbaP8TqZEjlrkWo5a5KhlzKKWOHRzaB_KBsxx5OAhAvd7AOIxNha8DNpCq8FYH-8vjbN_9f8CFGKgVw</recordid><startdate>200607</startdate><enddate>200607</enddate><creator>Özkaya, Gülşen</creator><creator>Shorbagi, Ali</creator><creator>Ülger, Zekeriya</creator><creator>Saglam, Arzu</creator><creator>Aybar, Melda</creator><creator>Şardan, Yeşim Çetinkaya</creator><creator>Uzun, Ömrüm</creator><general>Elsevier Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QL</scope><scope>C1K</scope><scope>7X8</scope></search><sort><creationdate>200607</creationdate><title>Invasive group A streptococcal infection with pancarditis caused by a new emm-type 12 allele of Streptococcus pyogenes</title><author>Özkaya, Gülşen ; 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Streptococcus pyogenes-related invasive infections has occurred. It has been suggested that a host-related immunogenetic background, as well as bacterial virulence factors may play an important role in the outcome of streptococcal infections. Here, we present the first case of pancarditis in the literature caused by direct bacterial invasion due to a new
emm-type 12 allele of
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subjects | Adult Alleles Antigens, Bacterial - genetics Bacterial Outer Membrane Proteins - genetics Carrier Proteins - genetics emm-Type 12 allele Fatal Outcome Female Humans Invasive infection Myocarditis - microbiology Pancarditis Sepsis - microbiology Streptococcal Infections - microbiology Streptococcus pyogenes Streptococcus pyogenes - classification Streptococcus pyogenes - genetics Streptococcus pyogenes - isolation & purification |
title | Invasive group A streptococcal infection with pancarditis caused by a new emm-type 12 allele of Streptococcus pyogenes |
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