Vitamin C supplementation influences the antioxidant response and nitric oxide handling of erythrocytes and lymphocytes to diving apnea
Objective: We have investigated the influence of vitamin C diet supplementation on the antioxidant response and nitrite levels in lymphocytes and erythrocytes during diving apnea. Subjects: Seven male professional apnea divers participated in a double blind crossover study. Divers were randomly assi...
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| Veröffentlicht in: | European journal of clinical nutrition 2006-07, Vol.60 (7), p.838-846 |
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| description | Objective: We have investigated the influence of vitamin C diet supplementation on the antioxidant response and nitrite levels in lymphocytes and erythrocytes during diving apnea. Subjects: Seven male professional apnea divers participated in a double blind crossover study. Divers were randomly assigned to either vitamin C supplemented or placebo groups. The subjects did not take any other supplements than the ones provided for this study. Intervention: One group was supplemented with vitamin C capsules (1 g per day) for 7 days while the other group took a placebo composed of lactose. The usual dietary habits of participants were assessed using a self-reported 7-days 24-h recall before the day of the study. Blood samples were taken under basal conditions, immediately after diving apnea for 4 h and after 1 h of recovery. Results: Catalase activity increased in erythrocytes (23%) and superoxide dismutase increased in lymphocytes (35%) during the recovery only in the placebo group. Lymphocyte ascorbate levels increased in the supplemented group after diving (85%) and maintained high at recovery. Plasma nitrite levels increased about twofold in both groups during the recovery. Erythrocyte nitrite levels increased after diving (50%) and about twofold during the recovery in the supplemented group. Nitrite levels and iNOS levels in lymphocytes were higher in the placebo group than in the supplemented during the recovery. Erythrocyte carbonyl derivates were unchanged in all situations. Conclusions: Vitamin C supplementation influenced the antioxidant response and NO handling in erythrocytes and lymphocytes to the oxidative stress induced by hypoxia-reoxygenation. |
| doi_str_mv | 10.1038/sj.ejcn.1602388 |
| format | Article |
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Subjects: Seven male professional apnea divers participated in a double blind crossover study. Divers were randomly assigned to either vitamin C supplemented or placebo groups. The subjects did not take any other supplements than the ones provided for this study. Intervention: One group was supplemented with vitamin C capsules (1 g per day) for 7 days while the other group took a placebo composed of lactose. The usual dietary habits of participants were assessed using a self-reported 7-days 24-h recall before the day of the study. Blood samples were taken under basal conditions, immediately after diving apnea for 4 h and after 1 h of recovery. Results: Catalase activity increased in erythrocytes (23%) and superoxide dismutase increased in lymphocytes (35%) during the recovery only in the placebo group. Lymphocyte ascorbate levels increased in the supplemented group after diving (85%) and maintained high at recovery. Plasma nitrite levels increased about twofold in both groups during the recovery. Erythrocyte nitrite levels increased after diving (50%) and about twofold during the recovery in the supplemented group. Nitrite levels and iNOS levels in lymphocytes were higher in the placebo group than in the supplemented during the recovery. Erythrocyte carbonyl derivates were unchanged in all situations. Conclusions: Vitamin C supplementation influenced the antioxidant response and NO handling in erythrocytes and lymphocytes to the oxidative stress induced by hypoxia-reoxygenation.</description><identifier>ISSN: 0954-3007</identifier><identifier>EISSN: 1476-5640</identifier><identifier>DOI: 10.1038/sj.ejcn.1602388</identifier><identifier>PMID: 16482080</identifier><language>eng</language><publisher>London: Nature Publishing Group UK</publisher><subject>adults ; anaerobic conditions ; antioxidant activity ; Antioxidants ; Antioxidants - administration & dosage ; Antioxidants - metabolism ; Apnea ; Apnea - blood ; Apnea - metabolism ; apnea divers ; Ascorbic acid ; Ascorbic Acid - administration & dosage ; Ascorbic Acid - metabolism ; athletes ; athletic performance ; Biological and medical sciences ; Blood ; blood chemistry ; blood gases ; breathing ; Carbonyl compounds ; Carbonyls ; Catalase ; Catalase - metabolism ; Cell Hypoxia - drug effects ; Clinical Nutrition ; Clinical trials ; Cross-Over Studies ; diet ; Dietary Supplements ; Diving ; diving apnea ; Double-Blind Method ; Epidemiology ; Erythrocytes ; Erythrocytes - enzymology ; Erythrocytes - metabolism ; free diving ; Humans ; Hypoxia ; Immune system ; Internal Medicine ; Lactose ; Lymphocytes ; Lymphocytes - enzymology ; Lymphocytes - metabolism ; Male ; Medical sciences ; Medicine ; Medicine & Public Health ; men ; Metabolic Diseases ; Nitric oxide ; Nitric Oxide - metabolism ; Nitric Oxide Synthase Type II - metabolism ; Nitric-oxide synthase ; Nitrites ; original-article ; Oxidation ; Oxidation-Reduction ; Oxidative stress ; Oxidative Stress - drug effects ; Oxidative Stress - physiology ; oxygen ; Placebos ; Public Health ; Recovery ; Superoxide dismutase ; Superoxide Dismutase - metabolism ; Vitamin C ; vitamin supplements</subject><ispartof>European journal of clinical nutrition, 2006-07, Vol.60 (7), p.838-846</ispartof><rights>Springer Nature Limited 2006</rights><rights>2006 INIST-CNRS</rights><rights>COPYRIGHT 2006 Nature Publishing Group</rights><rights>Copyright Nature Publishing Group Jul 2006</rights><rights>Nature Publishing Group 2006.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c649t-6a7b8f71093169b907c965c933c0b1ee8bc0068c9ccbd02e3cf4a02feb78bec13</citedby><cites>FETCH-LOGICAL-c649t-6a7b8f71093169b907c965c933c0b1ee8bc0068c9ccbd02e3cf4a02feb78bec13</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1038/sj.ejcn.1602388$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1038/sj.ejcn.1602388$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,778,782,27911,27912,41475,42544,51306</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=17900224$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16482080$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Sureda, A</creatorcontrib><creatorcontrib>Batle, J.M</creatorcontrib><creatorcontrib>Tauler, P</creatorcontrib><creatorcontrib>Ferrer, M.D</creatorcontrib><creatorcontrib>Tur, J.A</creatorcontrib><creatorcontrib>Pons, A</creatorcontrib><title>Vitamin C supplementation influences the antioxidant response and nitric oxide handling of erythrocytes and lymphocytes to diving apnea</title><title>European journal of clinical nutrition</title><addtitle>Eur J Clin Nutr</addtitle><addtitle>Eur J Clin Nutr</addtitle><description>Objective: We have investigated the influence of vitamin C diet supplementation on the antioxidant response and nitrite levels in lymphocytes and erythrocytes during diving apnea. Subjects: Seven male professional apnea divers participated in a double blind crossover study. Divers were randomly assigned to either vitamin C supplemented or placebo groups. The subjects did not take any other supplements than the ones provided for this study. Intervention: One group was supplemented with vitamin C capsules (1 g per day) for 7 days while the other group took a placebo composed of lactose. The usual dietary habits of participants were assessed using a self-reported 7-days 24-h recall before the day of the study. Blood samples were taken under basal conditions, immediately after diving apnea for 4 h and after 1 h of recovery. Results: Catalase activity increased in erythrocytes (23%) and superoxide dismutase increased in lymphocytes (35%) during the recovery only in the placebo group. Lymphocyte ascorbate levels increased in the supplemented group after diving (85%) and maintained high at recovery. Plasma nitrite levels increased about twofold in both groups during the recovery. Erythrocyte nitrite levels increased after diving (50%) and about twofold during the recovery in the supplemented group. Nitrite levels and iNOS levels in lymphocytes were higher in the placebo group than in the supplemented during the recovery. Erythrocyte carbonyl derivates were unchanged in all situations. Conclusions: Vitamin C supplementation influenced the antioxidant response and NO handling in erythrocytes and lymphocytes to the oxidative stress induced by hypoxia-reoxygenation.</description><subject>adults</subject><subject>anaerobic conditions</subject><subject>antioxidant activity</subject><subject>Antioxidants</subject><subject>Antioxidants - administration & dosage</subject><subject>Antioxidants - metabolism</subject><subject>Apnea</subject><subject>Apnea - blood</subject><subject>Apnea - metabolism</subject><subject>apnea divers</subject><subject>Ascorbic acid</subject><subject>Ascorbic Acid - administration & dosage</subject><subject>Ascorbic Acid - metabolism</subject><subject>athletes</subject><subject>athletic performance</subject><subject>Biological and medical sciences</subject><subject>Blood</subject><subject>blood chemistry</subject><subject>blood gases</subject><subject>breathing</subject><subject>Carbonyl compounds</subject><subject>Carbonyls</subject><subject>Catalase</subject><subject>Catalase - metabolism</subject><subject>Cell Hypoxia - drug effects</subject><subject>Clinical Nutrition</subject><subject>Clinical trials</subject><subject>Cross-Over Studies</subject><subject>diet</subject><subject>Dietary Supplements</subject><subject>Diving</subject><subject>diving apnea</subject><subject>Double-Blind Method</subject><subject>Epidemiology</subject><subject>Erythrocytes</subject><subject>Erythrocytes - enzymology</subject><subject>Erythrocytes - metabolism</subject><subject>free diving</subject><subject>Humans</subject><subject>Hypoxia</subject><subject>Immune system</subject><subject>Internal Medicine</subject><subject>Lactose</subject><subject>Lymphocytes</subject><subject>Lymphocytes - enzymology</subject><subject>Lymphocytes - metabolism</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>men</subject><subject>Metabolic Diseases</subject><subject>Nitric oxide</subject><subject>Nitric Oxide - metabolism</subject><subject>Nitric Oxide Synthase Type II - metabolism</subject><subject>Nitric-oxide synthase</subject><subject>Nitrites</subject><subject>original-article</subject><subject>Oxidation</subject><subject>Oxidation-Reduction</subject><subject>Oxidative stress</subject><subject>Oxidative Stress - drug effects</subject><subject>Oxidative Stress - physiology</subject><subject>oxygen</subject><subject>Placebos</subject><subject>Public Health</subject><subject>Recovery</subject><subject>Superoxide dismutase</subject><subject>Superoxide Dismutase - metabolism</subject><subject>Vitamin C</subject><subject>vitamin supplements</subject><issn>0954-3007</issn><issn>1476-5640</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2006</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNp9k01v1DAQhiMEosvCmRMQgai4ZDtOvE58rFZ8SZU4QLlGjjPZeJXYqe0g9hfwt3GUoC2oRT5YnveZeeXxOIqeE9gQyIoLd9jgQeoNYZBmRfEgWhGas2TLKDyMVsC3NMkA8rPoiXMHgCDm6ePojDBapFDAKvr1XXnRKx3vYjcOQ4c9ai-8MjpWuulG1BJd7FuMhQ7Rn6oOe2zRDUa7KVjHWnmrZDxpGLch0im9j00Toz361hp59KHERHbHfmiXszdxrX5MpBg0iqfRo0Z0Dp8t-zq6_vD-2-5TcvXl4-fd5VUiGeU-YSKviiYnwDPCeMUhl5xtJc8yCRVBLCoJwArJpaxqSDGTDRWQNljlRYWSZOvofK47WHMzovNlr5zErhMazehKVjCgWcYC-O6_IKGMbiG0PQ3om3_QgxmtDtcoU0bTHDIeaq6j1_dShDOWp2RyTWZoLzoswwsYb4Xco0YrOqOxUSF8STjlFCgrAr-5gw-rxl7JOxPObyW0KDrfOtON04u7v8GLGZTWOGexKQeremGPJYFymr3SHcpp9spl9kLGy-WCY9VjfeKXYQvA2wUQToqusUJL5U5cziG0c-oUzJwLkt6jPXXqfu8Xc4oWfrR4y_uP_mrWG2FKsbfB9vprCmT6HCxYQvYbHZQGEQ</recordid><startdate>20060701</startdate><enddate>20060701</enddate><creator>Sureda, A</creator><creator>Batle, J.M</creator><creator>Tauler, P</creator><creator>Ferrer, M.D</creator><creator>Tur, J.A</creator><creator>Pons, A</creator><general>Nature Publishing Group UK</general><general>Nature Publishing</general><general>Nature Publishing Group</general><scope>FBQ</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QP</scope><scope>7RV</scope><scope>7TK</scope><scope>7X2</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>AN0</scope><scope>ATCPS</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB0</scope><scope>LK8</scope><scope>M0K</scope><scope>M0S</scope><scope>M1P</scope><scope>M2O</scope><scope>M7P</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>Q9U</scope><scope>7T5</scope><scope>H94</scope><scope>7X8</scope></search><sort><creationdate>20060701</creationdate><title>Vitamin C supplementation influences the antioxidant response and nitric oxide handling of erythrocytes and lymphocytes to diving apnea</title><author>Sureda, A ; Batle, J.M ; Tauler, P ; Ferrer, M.D ; Tur, J.A ; Pons, A</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c649t-6a7b8f71093169b907c965c933c0b1ee8bc0068c9ccbd02e3cf4a02feb78bec13</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2006</creationdate><topic>adults</topic><topic>anaerobic conditions</topic><topic>antioxidant activity</topic><topic>Antioxidants</topic><topic>Antioxidants - administration & dosage</topic><topic>Antioxidants - metabolism</topic><topic>Apnea</topic><topic>Apnea - blood</topic><topic>Apnea - metabolism</topic><topic>apnea divers</topic><topic>Ascorbic acid</topic><topic>Ascorbic Acid - administration & dosage</topic><topic>Ascorbic Acid - metabolism</topic><topic>athletes</topic><topic>athletic performance</topic><topic>Biological and medical sciences</topic><topic>Blood</topic><topic>blood chemistry</topic><topic>blood gases</topic><topic>breathing</topic><topic>Carbonyl compounds</topic><topic>Carbonyls</topic><topic>Catalase</topic><topic>Catalase - metabolism</topic><topic>Cell Hypoxia - drug effects</topic><topic>Clinical Nutrition</topic><topic>Clinical trials</topic><topic>Cross-Over Studies</topic><topic>diet</topic><topic>Dietary Supplements</topic><topic>Diving</topic><topic>diving apnea</topic><topic>Double-Blind Method</topic><topic>Epidemiology</topic><topic>Erythrocytes</topic><topic>Erythrocytes - enzymology</topic><topic>Erythrocytes - metabolism</topic><topic>free diving</topic><topic>Humans</topic><topic>Hypoxia</topic><topic>Immune system</topic><topic>Internal Medicine</topic><topic>Lactose</topic><topic>Lymphocytes</topic><topic>Lymphocytes - enzymology</topic><topic>Lymphocytes - metabolism</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>men</topic><topic>Metabolic Diseases</topic><topic>Nitric oxide</topic><topic>Nitric Oxide - metabolism</topic><topic>Nitric Oxide Synthase Type II - metabolism</topic><topic>Nitric-oxide synthase</topic><topic>Nitrites</topic><topic>original-article</topic><topic>Oxidation</topic><topic>Oxidation-Reduction</topic><topic>Oxidative stress</topic><topic>Oxidative Stress - drug effects</topic><topic>Oxidative Stress - physiology</topic><topic>oxygen</topic><topic>Placebos</topic><topic>Public Health</topic><topic>Recovery</topic><topic>Superoxide dismutase</topic><topic>Superoxide Dismutase - metabolism</topic><topic>Vitamin C</topic><topic>vitamin supplements</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Sureda, A</creatorcontrib><creatorcontrib>Batle, J.M</creatorcontrib><creatorcontrib>Tauler, P</creatorcontrib><creatorcontrib>Ferrer, M.D</creatorcontrib><creatorcontrib>Tur, J.A</creatorcontrib><creatorcontrib>Pons, A</creatorcontrib><collection>AGRIS</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Nursing & Allied Health Database</collection><collection>Neurosciences Abstracts</collection><collection>Agricultural Science Collection</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest One Sustainability</collection><collection>ProQuest Central UK/Ireland</collection><collection>British Nursing Database</collection><collection>Agricultural & Environmental Science Collection</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>ProQuest Biological Science Collection</collection><collection>Agricultural Science Database</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Research Library</collection><collection>Biological Science Database</collection><collection>Research Library (Corporate)</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central Basic</collection><collection>Immunology Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>European journal of clinical nutrition</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Sureda, A</au><au>Batle, J.M</au><au>Tauler, P</au><au>Ferrer, M.D</au><au>Tur, J.A</au><au>Pons, A</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Vitamin C supplementation influences the antioxidant response and nitric oxide handling of erythrocytes and lymphocytes to diving apnea</atitle><jtitle>European journal of clinical nutrition</jtitle><stitle>Eur J Clin Nutr</stitle><addtitle>Eur J Clin Nutr</addtitle><date>2006-07-01</date><risdate>2006</risdate><volume>60</volume><issue>7</issue><spage>838</spage><epage>846</epage><pages>838-846</pages><issn>0954-3007</issn><eissn>1476-5640</eissn><abstract>Objective: We have investigated the influence of vitamin C diet supplementation on the antioxidant response and nitrite levels in lymphocytes and erythrocytes during diving apnea. Subjects: Seven male professional apnea divers participated in a double blind crossover study. Divers were randomly assigned to either vitamin C supplemented or placebo groups. The subjects did not take any other supplements than the ones provided for this study. Intervention: One group was supplemented with vitamin C capsules (1 g per day) for 7 days while the other group took a placebo composed of lactose. The usual dietary habits of participants were assessed using a self-reported 7-days 24-h recall before the day of the study. Blood samples were taken under basal conditions, immediately after diving apnea for 4 h and after 1 h of recovery. Results: Catalase activity increased in erythrocytes (23%) and superoxide dismutase increased in lymphocytes (35%) during the recovery only in the placebo group. Lymphocyte ascorbate levels increased in the supplemented group after diving (85%) and maintained high at recovery. Plasma nitrite levels increased about twofold in both groups during the recovery. Erythrocyte nitrite levels increased after diving (50%) and about twofold during the recovery in the supplemented group. Nitrite levels and iNOS levels in lymphocytes were higher in the placebo group than in the supplemented during the recovery. Erythrocyte carbonyl derivates were unchanged in all situations. Conclusions: Vitamin C supplementation influenced the antioxidant response and NO handling in erythrocytes and lymphocytes to the oxidative stress induced by hypoxia-reoxygenation.</abstract><cop>London</cop><pub>Nature Publishing Group UK</pub><pmid>16482080</pmid><doi>10.1038/sj.ejcn.1602388</doi><tpages>9</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0954-3007 |
| ispartof | European journal of clinical nutrition, 2006-07, Vol.60 (7), p.838-846 |
| issn | 0954-3007 1476-5640 |
| language | eng |
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| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Springer Nature - Complete Springer Journals; Nature Journals Online |
| subjects | adults anaerobic conditions antioxidant activity Antioxidants Antioxidants - administration & dosage Antioxidants - metabolism Apnea Apnea - blood Apnea - metabolism apnea divers Ascorbic acid Ascorbic Acid - administration & dosage Ascorbic Acid - metabolism athletes athletic performance Biological and medical sciences Blood blood chemistry blood gases breathing Carbonyl compounds Carbonyls Catalase Catalase - metabolism Cell Hypoxia - drug effects Clinical Nutrition Clinical trials Cross-Over Studies diet Dietary Supplements Diving diving apnea Double-Blind Method Epidemiology Erythrocytes Erythrocytes - enzymology Erythrocytes - metabolism free diving Humans Hypoxia Immune system Internal Medicine Lactose Lymphocytes Lymphocytes - enzymology Lymphocytes - metabolism Male Medical sciences Medicine Medicine & Public Health men Metabolic Diseases Nitric oxide Nitric Oxide - metabolism Nitric Oxide Synthase Type II - metabolism Nitric-oxide synthase Nitrites original-article Oxidation Oxidation-Reduction Oxidative stress Oxidative Stress - drug effects Oxidative Stress - physiology oxygen Placebos Public Health Recovery Superoxide dismutase Superoxide Dismutase - metabolism Vitamin C vitamin supplements |
| title | Vitamin C supplementation influences the antioxidant response and nitric oxide handling of erythrocytes and lymphocytes to diving apnea |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-15T12%3A37%3A38IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_proqu&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Vitamin%20C%20supplementation%20influences%20the%20antioxidant%20response%20and%20nitric%20oxide%20handling%20of%20erythrocytes%20and%20lymphocytes%20to%20diving%20apnea&rft.jtitle=European%20journal%20of%20clinical%20nutrition&rft.au=Sureda,%20A&rft.date=2006-07-01&rft.volume=60&rft.issue=7&rft.spage=838&rft.epage=846&rft.pages=838-846&rft.issn=0954-3007&rft.eissn=1476-5640&rft_id=info:doi/10.1038/sj.ejcn.1602388&rft_dat=%3Cgale_proqu%3EA194940468%3C/gale_proqu%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=219667216&rft_id=info:pmid/16482080&rft_galeid=A194940468&rfr_iscdi=true |