Prolonged recovery of retinal structure/function after gene therapy in an Rs1h-deficient mouse model of x-linked juvenile retinoschisis

X-linked juvenile retinoschisis (RS) is a common cause of juvenile macular degeneration in males. RS is characterized by cystic spoke-wheel-like maculopathy, peripheral schisis, and a negative (b-wave more reduced than a-wave) electroretinogram (ERG). These symptoms are due to mutations in the RS1 g...

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Veröffentlicht in:Molecular therapy 2005-10, Vol.12 (4), p.644-651
Hauptverfasser: Min, Seok H, Molday, Laurie L, Seeliger, Mathias W, Dinculescu, Astra, Timmers, Adrian M, Janssen, Andreas, Tonagel, Felix, Tanimoto, Naoyuki, Weber, Bernhard H F, Molday, Robert S, Hauswirth, William W
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Sprache:eng
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