Down-regulation of MHC class I is a property common to papillomavirus E5 proteins

The E5 protein family of papillomaviruses comprises small hydrophobic proteins which are associated with the cell endomembrane compartments. The functions of the E5 proteins, particularly those of HPV, are still far from clear. We have reported that the E5 proteins of BPV-1, BPV-4, HPV-16 and HPV-6...

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Veröffentlicht in:	Virus research 2006-09, Vol.120 (1), p.208-211
Hauptverfasser:	Ashrafi, G.H., Brown, D.R., Fife, K.H., Campo, M.S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell Line Down-Regulation E5-heavy chain interaction Histocompatibility Antigens Class I - metabolism HPV-83 Humans Keratinocytes MHC class I down-regulation Oncogene Proteins, Viral - genetics Oncogene Proteins, Viral - physiology Papillomaviridae - immunology Papillomavirus Papillomavirus Infections - immunology Transfection Viral Interference
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